Background Asthma guidelines suggest reducing controller medications when asthma is
stable. Methods The purpose of the study is to estimate the risk of asthma exacerbation in …

Background: International guidelines recommend regular treatment with inhaled
glucocorticoids for children with frequent wheezing; however, prn inhaled bronchodilator …

Background In people with mild asthma poor adherence to regular therapy is common and
increases the risk of exacerbations, morbidity and mortality. The use of fixed-dose …

Objective Overuse of short-acting bronchodilators is internationally recognised as a marker
of poor asthma control, high healthcare use and increased risk of asthma death. Young …

For the last three decades, the guidelines for asthma management have supported a
stepwise therapeutic approach, based on the administration of controller medications …

the potential side-effects of daily treatment with ICS. Additionally, as appropriately
mentioned by Reddel and colleagues, 8 patients should also be offered the alternative as …

A stepwise approach to the pharmacological treatment of asthma is a key feature of current
asthma guidelines [1–4]. Through algorithms, treatment intensity is “stepped up” to obtain …

Background In many patients with mild asthma, the low frequency of symptoms and the
episodic nature of exacerbations make adherence to regular maintenance treatment difficult …

Inhaled corticosteroids (ICSs) have been recommended as a maintenance treatment, either
alone or together with long-acting inhaled β2-agonists, for all asthma patients. Short-acting …

Background In the phase 3 MANDALA trial, as-needed albuterol-budesonide pressurized
metered-dose inhaler significantly reduced severe exacerbation risk vs as-needed albuterol …