Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects
Chronic stressful life events are risk factors for developing major depression, the
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …
Autonomic dysfunction and heart rate variability in depression
A Sgoifo, L Carnevali, MA Pico Alfonso, M Amore - Stress, 2015 - Taylor & Francis
Depression occurs in people of all ages across all world regions; it is the second leading
cause of disability and its global burden increased by 37.5% between 1990 and 2010 …
cause of disability and its global burden increased by 37.5% between 1990 and 2010 …
Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats
Y Pan, XY Chen, QY Zhang, LD Kong - Brain, behavior, and immunity, 2014 - Elsevier
Depression is an inflammatory disorder. Pro-inflammatory cytokine interleukin-1 beta (IL-1β)
may play a pivotal role in the central nervous system (CNS) inflammation of depression …
may play a pivotal role in the central nervous system (CNS) inflammation of depression …
Stress, depression and cardiovascular dysregulation: a review of neurobiological mechanisms and the integration of research from preclinical disease models
AJ Grippo, AK Johnson - Stress, 2009 - Taylor & Francis
Bidirectional associations between mood disorders and cardiovascular diseases are
extensively documented. However, the precise physiological and biochemical mechanisms …
extensively documented. However, the precise physiological and biochemical mechanisms …
[HTML][HTML] Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression
This study evaluated the chronic effects of fluoxetine, a commonly prescribed SSRI
antidepressant, on the peripheral and central levels of inflammatory cytokines including IL …
antidepressant, on the peripheral and central levels of inflammatory cytokines including IL …
[HTML][HTML] Chronic stress impacts the cardiovascular system: animal models and clinical outcomes
Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …
cardiovascular diseases are among the most important group of psychosomatic diseases …
Amygdala-ventral pallidum pathway decreases dopamine activity after chronic mild stress in rats
Background Major depressive disorder affects more than 15% of the population across their
lifespan. In this study, we used the well-characterized unpredictable chronic mild stress …
lifespan. In this study, we used the well-characterized unpredictable chronic mild stress …
Social isolation induces behavioral and neuroendocrine disturbances relevant to depression in female and male prairie voles
AJ Grippo, D Gerena, J Huang, N Kumar… - …, 2007 - Elsevier
Supportive social interactions may be protective against stressors and certain mental and
physical illness, while social isolation may be a powerful stressor. Prairie voles are socially …
physical illness, while social isolation may be a powerful stressor. Prairie voles are socially …
The involvement of TNF-α in cognitive dysfunction associated with major depressive disorder: an opportunity for domain specific treatments
B Bortolato, AF Carvalho… - Current …, 2015 - ingentaconnect.com
Major depressive disorder is a highly prevalent, chronic and recurring disorder, associated
with substantial impairment in cognitive and interpersonal functions. Accumulating evidence …
with substantial impairment in cognitive and interpersonal functions. Accumulating evidence …
Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation
AJ Grippo, DM Trahanas, RR Zimmerman II… - …, 2009 - Elsevier
Positive social interactions and social support may protect against various forms of mental
and physical illness, although the mechanisms for these effects are not well identified. The …
and physical illness, although the mechanisms for these effects are not well identified. The …