New psychoactive substances (NPS) are a heterogeneous group of substances. They are
associated with a number of health and social harms on an individual and societal level …

Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the
pancreas in individuals with genetic, environmental and/or other risk factors who develop …

Abdominal pain is the foremost complication of chronic pancreatitis (CP). Pain can be
related to recurrent or chronic inflammation, local complications or neurogenic mechanisms …

Opioids are the oldest and most potent drugs for the treatment of severe pain. Their clinical
application is undisputed in acute (eg, postoperative) and cancer pain, but their long-term …

Poorly controlled pain is a global public health issue. The personal, familial and societal
costs are immeasurable. Only a minority of European patients have access to a …

Importance Diacetylmorphine hydrochloride (the active ingredient in heroin), delivered
under supervision, is effective for the treatment of severe opioid use disorder. However …

Background Opioid use for chronic non‐cancer pain (CNCP) is complex. In the absence of
pan‐European guidance on this issue, a position paper was commissioned by the European …

Describing, understanding, and designing complex interaction networks within
macromolecular systems remain challenging in modern chemical research. Host–guest …

Acetaminophen (paracetamol) is the most commonly used analgesic worldwide and
recommended as first‐line treatment in all pain conditions by WHO. We performed a …

Introduction In the past decades, the opioid crisis has heavily impacted parts of the US
society and has been followed by an increase in the use of opioids worldwide. It is of …