The evolving landscape of antibody–drug conjugates: In depth analysis of recent research progress

JM Sasso, R Tenchov, R Bird, KA Iyer… - Bioconjugate …, 2023 - ACS Publications
Antibody–drug conjugates (ADCs) are targeted immunoconjugate constructs that integrate
the potency of cytotoxic drugs with the selectivity of monoclonal antibodies, minimizing …

Practical Approaches to Genetic Code Expansion with Aminoacyl-tRNA Synthetase/tRNA Pairs

AN Perdiguero, AD Liang - Chimia, 2024 - chimia.ch
Genetic code expansion (GCE) can enable the site-selective incorporation of non-canonical
amino acids (ncAAs) into proteins. GCE has advanced tremendously in the last decade and …

Chemical conjugation innovations for protein nanoparticles

MG Legendre, VH Pistilli, GS Demirer - Trends in Chemistry, 2024 - cell.com
Protein nanoparticles (PNPs) present versatile platforms for cargo delivery due to their
modularity, biocompatibility, and self-assembled structures. PNPs have benefited greatly …