PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis

J Straube, S Bukhari, S Lerrer, RJ Winchester… - Arthritis Research & …, 2024 - Springer
Background PD-1 is an immune checkpoint on T cells, and interventions to block this
receptor result in T cell activation and enhanced immune response to tumors and …

The effect of PD-1/PD-L1 signaling axis on the interaction between CD19+B cells and CD4+T cells in peripheral blood of patients with systemic lupus erythematosus

Z Xie, L Dai, H He, D Hong, H Tang, W Xu… - Advances in …, 2023 - SciELO Brasil
Background The defect of B cell self-tolerance and the continuous antigen presentation by T
cells (TCs) mediated by autoreactive B cells (BCs) play a key role in the occurrence and …

The role of post-transcriptional control of CD40L on the development of autoimmune disorders

D Prado De Maio - 2024 - rucore.libraries.rutgers.edu
Figure 0.1: B cell development........................................................................................................ 5
Figure 0.2: Network of cell signals and transcription factors regulating B cell activation and …

PROTECTIVE ROLES FOR INTERFERON-GAMMA IN ASTROCYTES DURING CHRONIC AUTOIMMUNITY

BC Smith - 2023 - rave.ohiolink.edu
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease of the central
nervous system (CNS). Infiltrating inflammatory immune cells perpetuate demyelination and …

The SLE Conundrum: A Comprehensive Analysis of Pathogenesis, Re-cent Developments, and the Future of Therapeutic Interventions

U Sharma - Critical Reviews™ in Immunology - dl.begellhouse.com
ABSTRACT Systemic Lupus Erythematosus (SLE) is a complex autoimmune disorder with
multifactorial interactions among various susceptibility factors. Significant strides have been …