Nearly all human complex traits and disease phenotypes exhibit some degree of sex
differences, including differences in prevalence, age of onset, severity or disease …

A rapidly developing paradigm for modern health care is a proactive and individualized
response to patients' symptoms, combining precision diagnosis and personalized treatment …

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

Group 2 innate lymphoid cells (ILC 2s) play critical roles in the induction of type 2
inflammation, response to parasite infection, metabolic homeostasis, and tissue repair …

Sex-related differences in asthma prevalence are well established and change through the
reproductive phases of life. As children, boys have increased prevalence of asthma …

Biological sex differences refer to differences between males and females caused by the sex
chromosome complement (that is, XY or XX), reproductive tissues (that is, the presence of …

Sex differences in the incidence and severity of respiratory virus infection are widely
documented in humans and murine models and correlate with sex biases in numbers and/or …

Biological sex, being female or male, broadly influences diverse immune phenotypes,
including immune responses to diseases at mucosal surfaces. Sex hormones, sex …

Group 2 innate lymphoid cells (ILC2s) are increasingly recognized as a key controller of type
2 inflammation, and are well known to be highly elevated in human airway type 2 …

Women have higher prevalence of asthma compared with men. In asthma, allergic airway
inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and …