Comparison of proportion of elevated carcinoembryonic antigen levels in patients with appendiceal and colorectal adenocarcinoma: A systematic review and meta …

AT Cristaudo, SB Jennings, DL Morris - Anticancer Research, 2022 - ar.iiarjournals.org
Background/Aim: The proportion of patients with liver metastases in patients with
appendiceal versus colorectal adenocarcinomas was 3.1 percent and 24 percent …

[HTML][HTML] Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer

R Sestito, R Cianfrocca, P Tocci, L Rosanò… - Communications …, 2020 - nature.com
Identification of regulatory mechanisms underlying the poor prognosis of ovarian cancer is
necessary for diagnostic and therapeutic implications. Here we show that endothelin A …

Epithelial–mesenchymal transition‐related serum markers ET‐1, IL‐8 and TGF‐β2 are elevated in a Finnish wet age‐related macular degeneration cohort

MPK Liukkonen, JJ Paterno, N Kivinen… - Acta …, 2022 - Wiley Online Library
Purpose It has been hypothesized that epithelial–mesenchymal transition (EMT) may occur
in the retinal pigment epithelium of advanced stage age‐related macular degeneration …

[HTML][HTML] Relevance of baseline carcinoembryonic antigen for first-line treatment against metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab …

JW Holch, I Ricard, S Stintzing… - European Journal of …, 2019 - Elsevier
Purpose Increased baseline carcinoembryonic antigen (CEA) serum level is associated with
inferior overall survival (OS) in metastatic colorectal cancer (mCRC). However, limited data …

[HTML][HTML] Effects of ADMA on gene expression and metabolism in serum-starved LoVo cells

N Zheng, K Wang, J He, Y Qiu, G Xie, M Su, W Jia… - Scientific reports, 2016 - nature.com
Serum starvation is a typical way for inducing tumor cell apoptosis and stress. Asymmetric
dimethylarginine (ADMA) is an endogenous metabolite. Our previous study reveals the …

[HTML][HTML] The prognostic role of inflammatory markers in patients with metastatic colorectal cancer treated with bevacizumab: A translational study [ASCENT]

SJ Clarke, M Burge, K Feeney, P Gibbs, K Jones… - PLoS …, 2020 - journals.plos.org
Background In spite of demonstrating prognostic and possibly predictive benefit in
retrospective cohorts and meta-analyses of cancer populations, including colorectal cancer …

[HTML][HTML] Suppressed endothelin-1 by anti-VEGF therapy is important for patients with BRVO-related macular edema to improve their vision

T Kida, J Flammer, H Oku, S Morishita, M Fukumoto… - EPMA Journal, 2016 - Springer
Background Branch retinal vein occlusion (BRVO) commonly occurs at the arteriovenous
crossing in the unilateral eye, and cardiovascular diseases can be risk factors of BRVO …

Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer

SP Gampenrieder, C Hufnagl… - The …, 2017 - nature.com
Biomarkers for bevacizumab efficacy in metastatic breast cancer (MBC) are of urgent need.
The genetic variability of genes involved in angiogenesis could explain the interpatient …

[PDF][PDF] Prognostische und prädiktive Faktoren beim metastasierten kolorektalen Karzinom unter Berücksichtigung innovativer Surrogatparameter für das …

J Holch - 2021 - edoc.ub.uni-muenchen.de
Mit der Einführung moderner und zielgerichteter Systemtherapie konnte das
Gesamtüberleben (engl. overall survival; OS) in dieser Situation auf über 30 Monate …

22 Optical Coherence Tomography and Anti-Vascular Endothelial Growth Factor Therapy

MR Thorell, PJ Rosenfeld - 2015 - thieme-connect.com
Vascular endothelial growth factor-A (VEGF) is the major cytokine responsible for
physiologic and pathological angiogenesis. Retinal diseases characterized by pathologic …