Multiscale Modeling of Respiratory Transport Phenomena and Intersubject Variability

SC Kassinos, J Sznitman - Annual Review of Fluid Mechanics, 2024 - annualreviews.org
Our understanding of respiratory flow phenomena has been consolidated over decades with
the exploration of in vitro and in silico canonical models that underscore the multiscale fluid …

[HTML][HTML] Obstructive and restrictive spirometry from school age to adulthood: three birth cohort studies

A Ullah, R Granell, S Haider, L Lowe… - …, 2024 - thelancet.com
Background Spirometric obstruction and restriction are two patterns of impaired lung
function which are predictive of poor health. We investigated the development of these …

Dysanapsis as a determinant of lung function in development and disease

EA McGinn, EW Mandell, BJ Smith… - American Journal of …, 2023 - atsjournals.org
Respiratory diseases in both children and adults are a major cause of morbidity and
mortality worldwide. Despite decades of research, mechanisms underlying the broad …

It is high time to discard a cut-off of 0.70 in the diagnosis of COPD

JY Choi, CK Rhee - Expert Review of Respiratory Medicine, 2024 - Taylor & Francis
Introduction Chronic obstructive pulmonary disease (COPD) has traditionally been
diagnosed based on the criterion of an FEV1/FVC< 0.70. However, this definition has …

Airway tree caliber and susceptibility to pollution-associated emphysema: MESA Air and Lung Studies

C Sack, M Wang, V Knutson, A Gassett… - American journal of …, 2024 - atsjournals.org
Rationale: Airway tree morphology varies in the general population and may modify the
distribution and uptake of inhaled pollutants. Objectives: We hypothesized that smaller …

[HTML][HTML] Investigating distributions of inhaled aerosols in the lungs of post-COVID-19 clusters through a unified imaging and modeling approach

X Zhang, F Li, PK Rajaraman, AP Comellas… - European Journal of …, 2024 - Elsevier
Background Recent studies, based on clinical data, have identified sex and age as
significant factors associated with an increased risk of long COVID. These two factors align …

Chest CT Airway and Vascular Measurements in Females with COPD or Long-COVID

HK Kooner, PV Wyszkiewicz… - COPD: Journal of …, 2024 - Taylor & Francis
Chest CT provides a way to quantify pulmonary airway and vascular tree measurements. In
patients with COPD, CT airway measurement differences in females are concomitant with …

The role of chest computed tomography in the evaluation and management of chronic obstructive pulmonary disease

RM Burkes, MA Zafar, RJ Panos - Current Opinion in Pulmonary …, 2024 - journals.lww.com
The role of chest computed tomography in the evaluation and... : Current Opinion in Pulmonary
Medicine The role of chest computed tomography in the evaluation and management of chronic …

Unsupervised Airway Tree Clustering with Deep Learning: The Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study

SN Naik, ED Angelini, RG Barr, N Allen… - arXiv preprint arXiv …, 2024 - arxiv.org
High-resolution full lung CT scans now enable the detailed segmentation of airway trees up
to the 6th branching generation. The airway binary masks display very complex tree …

[HTML][HTML] An Issue of Caliber: The Airway Tree and Air Pollution Susceptibility

JH Brems, S Raju - American Journal of Respiratory and Critical …, 2024 - atsjournals.org
Globally, air pollution may present the largest environmental threat to health.(1) Higher
ambient air pollution exposure contributes to accelerated lung function decline, emphysema …