[HTML][HTML] Resurgence of omicron BA. 2 in SARS-CoV-2 infection-naive Hong Kong
Hong Kong experienced a surge of Omicron BA. 2 infections in early 2022, resulting in one
of the highest per-capita death rates of COVID-19. The outbreak occurred in a dense …
of the highest per-capita death rates of COVID-19. The outbreak occurred in a dense …
[HTML][HTML] Reply to: Population genetic considerations regarding the interpretation of within-patient SARS-CoV-2 polymorphism data
In comments on our paper “Within-host genetic diversity of SARS-CoV-2 lineages in
unvaccinated and vaccinated individuals,” Soni et al. argue that the methods we employed …
unvaccinated and vaccinated individuals,” Soni et al. argue that the methods we employed …
[HTML][HTML] Distinctive serotypes of SARS-related coronaviruses defined by convalescent sera from unvaccinated individuals
Multiple Omicron sub-lineages have emerged, with Omicron XBB and XBB. 1.5 subvariants
becoming the dominant variants globally at the time of this study. The key feature of new …
becoming the dominant variants globally at the time of this study. The key feature of new …
[HTML][HTML] SARS-CoV-2 entry into and evolution within a skilled nursing facility
NR Sexton, PJ Cline, EN Gallichotte, E Fitzmeyer… - Scientific Reports, 2023 - nature.com
SARS-CoV-2 belongs to the family Coronaviridae which includes multiple human pathogens
that have an outsized impact on aging populations. As a novel human pathogen, SARS-CoV …
that have an outsized impact on aging populations. As a novel human pathogen, SARS-CoV …
[HTML][HTML] Viral and host factors associated with SARS-CoV-2 disease severity in Georgia, USA
LR Carmola, AD Roebling, D Khosravi, RM Langsjoen… - medRxiv, 2023 - ncbi.nlm.nih.gov
While SARS-CoV-2 vaccines have shown strong efficacy, their suboptimal uptake combined
with the continued emergence of new viral variants raises concerns about the ongoing and …
with the continued emergence of new viral variants raises concerns about the ongoing and …
A simulation framework for modeling the within-patient evolutionary dynamics of SARS-CoV-2
The global impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
led to considerable interest in detecting novel beneficial mutations and other genomic …
led to considerable interest in detecting novel beneficial mutations and other genomic …
Host-Pathogen Interaction: Biology and Public Health
Interactions between host and pathogenic microorganisms are common in nature and have
a significant impact on host health, often leading to several types of infections. These …
a significant impact on host health, often leading to several types of infections. These …
[HTML][HTML] Viral expansion after transfer is a primary driver of influenza A virus transmission bottlenecks
For many viruses, narrow bottlenecks acting during transmission sharply reduce genetic
diversity in a recipient host relative to the donor. Since genetic diversity represents adaptive …
diversity in a recipient host relative to the donor. Since genetic diversity represents adaptive …
Molecular evolution and adaptation of SARS-CoV-2 omicron XBB sub-lineage Spike protein under African selection pressure.
MS Kambarami, G Ngorima, PK Moyo… - Access …, 2023 - microbiologyresearch.org
The Omicron variant of SARS-CoV-2, which is a cause of concern, has various mutations in
its spike protein. This protein is responsible for both viral infection and immunity. We have …
its spike protein. This protein is responsible for both viral infection and immunity. We have …
Integrating Machine Learning-Enhanced Immunopeptidomics and SARS-CoV-2 Population-Scale Analyses Unveils Novel Antigenic Features for Next-Generation …
Next-generation T-cell-directed vaccines for COVID-19 aim to induce durable T-cell
immunity against circulating and future hypermutated SARS-CoV-2 variants. Mass …
immunity against circulating and future hypermutated SARS-CoV-2 variants. Mass …