Tissue engineering (TE) and regenerative medicine integrate information and technology
from various fields to restore/replace tissues and damaged organs for medical treatments …

Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …

Treating large bone defects, known as critical-sized defects (CSDs), is challenging because
they are not spontaneously healed by the patient's body. Due to the limitations associated …

Physically cross-linked hydrogels are used as scaffolds in tissue engineering applications
because they are easily produced and avoid the potential toxicity produced by chemical …

The field of machine learning is comprised of techniques, which have proven powerful
approaches to knowledge discovery and construction of 'digital twins' in the highly …

Co-culturing of cells in in vitro tissue models is widely used to study how they interact with
each other. These models serve to represent a variety of processes in the human body such …

Abstract 3D bioprinting is emerging as a promising technology for fabricating complex tissue
constructs with tailored biological components and mechanical properties. Recent advances …

There has been considerable advancement over the last few years in the treatment of
osteoarthritis, common chronic disease and a major cause of disability in older adults. In this …

Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Tendon injuries are a global health problem that affects millions of people annually. The
properties of tendons make their natural rehabilitation a very complex and long-lasting …