Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …

Oxidative stress has been implicated to play a crucial role in the pathogenesis of a number
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …

Aging affects functional connectivity between brain areas, however, a complete picture of
how aging affects integration of information within and between functional networks is …

CDS is an underdiagnosed behavioral problem that affects a substantial number of aged
pets. Because changes in behavior are often early indicators of medical or behavior …

Oxidative stress has been implicated in the pathogenesis of a number of diseases including
Alzheimer's disease (AD). The oxidative stress hypothesis of AD pathogenesis, in part, is …

According to the WHO, the proportion of people over 60 years is increasing and expected to
reach 22% of total world's population in 2050. In parallel, recent animal demographic …

The aged dog naturally develops cognitive decline in many different domains (including
learning and memory) but also exhibits human-like individual variability in the aging …

A decline in the physical or mental health of older dogs can be a challenge for the owners,
whose relationship with their dog is compromised by the cognitive and behavioral changes …

Canine cognitive dysfunction (CCD) is the canine analog of human Alzheimer disease (AD).
CCD is common in older dogs, particularly those more than 8 years old. Slowly progressive …

The effectiveness of two interventions, dietary fortification with antioxidants and a program of
behavioral enrichment, was assessed in a longitudinal study of cognitive aging in beagle …