Temporins are short peptides secreted by frogs from all over the world. They exert
antimicrobial activity, mainly against Gram-positive bacteria, including resistant pathogens; …

De novo sequencing of any novel peptide/protein is a difficult task. Full sequence coverage,
isomeric amino acid residues, inter-and intramolecular S–S bonds, and numerous other post …

Disulfide bonds formed by a pair of cysteine residues in the peptides' backbone represent a
certain problem for their sequencing by means of mass spectrometry. As a rule, in …

Amphibians are one of the oldest classes of vertebrates inhabiting the Earth. Meanwhile, the
only weapon their majority possess involves exclusively peptide cocktail secreted by their …

The skin of amphibians is a rich source of peptides with a wide range of biological activities.
They are stored in secretory granules in an inactive form. Upon stimulation, they are …

Peptides released on frogs' skin in a stress situation represent their only weapon against
micro-organisms and predators. Every species and even population of frog possesses its …

The field of peptidomics has been under development since its start more than 20 years ago.
In this chapter we provide a personal outlook for future directions in this field. The …

Natural peptides secreted under stress conditions by many organisms are bioactive
molecules with a broad spectrum of activities. These molecules could become potential …

The study of urinary peptidome is an important area of research, which concerns the
characterization of endogenous peptides, as well as the identification of biomarkers for a …