The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

Objectives Candidaemia is a serious hazard to hospitalized patients, but European
epidemiological data are restricted to national studies focusing on Northern Europe …

Candida species cause frequent infections owing to their ability to form biofilms—surface-
associated microbial communities—primarily on implanted medical devices. Increasingly …

The incidence of invasive mycoses is increasing, especially among patients who are
immunocompromised or hospitalized with serious underlying diseases. Such infections may …

A substantial proportion of patients become colonised with Candida spp during hospital
stay, but only few subsequently develop severe infection. Clinical signs of severe infection …

Biofilms are dynamic microbial communities in which transitions between planktonic and
sessile modes of growth occur interchangeably in response to different environmental cues …

Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …

It is widely assumed that the ability of Candida albicans to switch between different
morphologies is required for pathogenesis. However, most virulence studies have used …

In recent years there has been an increasing appreciation that microbial biofilms are
ubiquitous, which has resulted in a number of studies on infectious diseases from a biofilm …

For many years, bacterial cells were considered primarily as selfish individuals, but, in
recent years, it has become evident that, far from operating in isolation, they coordinate …