Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid
asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly …

Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …

B‑cell acute lymphoblastic lymphoma (B‑ALL) is a disease found mainly in children and in
young adults. B‑ALL is characterized by the rapid proliferation of poorly differentiated …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer and accounts for
about a quarter of adult acute leukemias, and features different outcomes depending on the …

Cellular heterogeneity is a major cause of treatment resistance in cancer. Despite recent
advances in single-cell genomic and transcriptomic sequencing, it remains difficult to relate …

Currently, new advancements in the area of nanotechnology opened up new prospects in
the field of medicine that could provide us with a solution for numerous medical …

Background Attention-deficit/hyperactivity disorder is characterized by neurobiological
heterogeneity, possibly explaining why not all patients benefit from a given treatment. As a …

Liver cancer and leukemia are the fourth and first causes, respectively, of cancer death in
children and adults worldwide. Moreover, cancer treatments, although beneficial, remain …

Graft-versus-host disease (GVHD) occasionally leads to morbidity and mortality but is
thought to reduce the risk of relapses in patients with a hematological malignancy. However …

Simple Summary Reduced response to glucocorticoids (GCs, such as dexamethasone,
Dex), first-line drugs employed during therapy induction, is considered a poor prognosis …