Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

Synthetic molecular robots can execute sophisticated molecular tasks at nanometer
resolution. However, a molecular robot capable of controlling cellular behavior remains …

In the last two decades, DNA has attracted significant attention toward the development of
materials at the nanoscale for emerging applications due to the unparalleled versatility and …

A guide RNA (gRNA) directs the function of a CRISPR protein effector to a target gene of
choice, providing a versatile programmable platform for engineering diverse modes of …

Immunotherapy is one of the most promising clinical modalities for the treatment of
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …

Synthetically directing T‐cells against tumors emerges as a promising strategy in
immunotherapy, while it remains challenging to smartly engage T cells with tunable immune …

Abstract Nitric oxide synthase 3 (NOS3) produces the gasotransmitter nitric oxide (NO),
which drives critical cellular signaling pathways by S-nitrosylating target proteins …

Cancer is the 3 rd leading cause of death globally and the countries with low-to-middle
income account for most cancer cases. The current diagnostic tools including imaging …

The precise regulation of interactions of specific immunological components is crucial for
controllable immunomodulation, yet it remains a great challenge. With the assistance of …