[HTML][HTML] Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response
SY Cai, X Ouyang, Y Chen, CJ Soroka, J Wang… - JCI insight, 2017 - ncbi.nlm.nih.gov
Mechanisms of bile acid–induced (BA-induced) liver injury in cholestasis are controversial,
limiting development of new therapies. We examined how BAs initiate liver injury using …
limiting development of new therapies. We examined how BAs initiate liver injury using …
Interleukin‐8: a critical chemokine in biliary atresia
R Dong, S Zheng - Journal of gastroenterology and hepatology, 2015 - Wiley Online Library
Biliary atresia (BA) is characterized by periductular inflammation and fibrosis and is
associated with the progressive obliteration of the bile ducts. The induction and …
associated with the progressive obliteration of the bile ducts. The induction and …
[HTML][HTML] Progress in biomarkers related to biliary atresia
F Kong, R Dong, G Chen, S Sun, Y Yang… - Journal of Clinical …, 2024 - ncbi.nlm.nih.gov
Biliary atresia (BA) is a congenital cholestatic disease that can seriously damage children's
liver function. It is one of the main reasons for liver transplantation in children. Early …
liver function. It is one of the main reasons for liver transplantation in children. Early …
[PDF][PDF] Gene expression signature for biliary atresia and a role for interleukin‐8 in pathogenesis of experimental disease
K Bessho, R Mourya, P Shivakumar, S Walters… - …, 2014 - Wiley Online Library
Biliary atresia (BA) is a progressive fibroinflammatory obstruction of extrahepatic bile ducts
that presents as neonatal cholestasis. Due to the overlap in clinical, biochemical, and …
that presents as neonatal cholestasis. Due to the overlap in clinical, biochemical, and …
Loss of ileum decreases serum fibroblast growth factor 19 in relation to liver inflammation and fibrosis in pediatric onset intestinal failure
A Mutanen, J Lohi, P Heikkilä, H Jalanko… - Journal of …, 2015 - Elsevier
Background & Aims The pathogenesis of intestinal failure (IF) associated liver disease
(IFALD) is uncertain, we therefore investigated the role of FGF19 and pro-inflammatory …
(IFALD) is uncertain, we therefore investigated the role of FGF19 and pro-inflammatory …
Distinct plasma bile acid profiles of biliary atresia and neonatal hepatitis syndrome
K Zhou, J Wang, G Xie, Y Zhou, W Yan… - Journal of proteome …, 2015 - ACS Publications
Biliary atresia (BA) is a severe chronic cholestasis disorder of infants that leads to death if
not treated on time. Neonatal hepatitis syndrome (NHS) is another leading cause of …
not treated on time. Neonatal hepatitis syndrome (NHS) is another leading cause of …
Gut microbial profile in biliary atresia: a case‐control study
J Wang, T Qian, J Jiang, Y Yang, Z Shen… - Journal of …, 2020 - Wiley Online Library
Abstract Background and Aim Biliary atresia (BA) is a progressive fibro‐inflammatory
cholangiopathy with an unclear etiology. Various liver disorders are associated with an …
cholangiopathy with an unclear etiology. Various liver disorders are associated with an …
Diagnostic values of plasma matrix metalloproteinase-7, interleukin-8, and gamma-glutamyl transferase in biliary atresia
B Wu, Y Zhou, X Tian, W Cai, Y Xiao - European journal of pediatrics, 2022 - Springer
Biliary atresia (BA) is a severe cholestatic liver disease in children featuring cholestasis and
liver fibrosis. The early diagnosis of BA is still challenging. This study aimed to evaluate the …
liver fibrosis. The early diagnosis of BA is still challenging. This study aimed to evaluate the …
Circulating microRNA is a biomarker of biliary atresia
Objective: The lack of reliable noninvasive diagnostic biomarkers of biliary atresia (BA)
results in delayed diagnosis and worsened patient outcome. Circulating microRNAs …
results in delayed diagnosis and worsened patient outcome. Circulating microRNAs …
Prophylactic antibiotics to prevent cholangitis in children with biliary atresia after Kasai portoenterostomy: a meta-analysis
FS Alatas, G Lazarus, MC Junaidi… - Journal of pediatric …, 2023 - journals.lww.com
Objectives: A connection between the bowel and bile ducts after the Kasai
hepatoportoenterostomy (HPE) procedure poses a risk of ascending cholangitis. There were …
hepatoportoenterostomy (HPE) procedure poses a risk of ascending cholangitis. There were …