Breast cancer (BC) is mostly observed in women and is responsible for huge mortality in
women subjects globally. Due to the continued development of drug resistance and other …

Simple Summary The p53 family is a complex family of transcription factors with different
cellular functions that are involved in several physiological processes. A massive amount of …

Gastric cancer (GC) is commonly treated by chemotherapy using 5-fluorouracil (5-FU)
derivatives and platinum combination, but predictive biomarker remains lacking. We develop …

In the present study, chitosan and polyvinyl alcohol (PVA) were blended with different
concentrations of sodium montmorillonite (Na+ MMT) clay solution by a solvent casting …

Proapoptotic drugs such as docetaxel displayed least toxicity and highest antitumor efficacy
following dosing during the circadian rest phase in mice, suggesting that cell cycle and …

New anticancer agents with lower toxicity have been always urged because of drug
resistance associated with overused chemotherapy agents. In this study, steviol, a colonic …

Selective inhibition of targeted protein kinases is an effective therapeutic approach for
treatment of human malignancies, which interferes phosphorylation of cellular substrates …

Background: Loss of function of the p53 gene is implicated in defective apoptotic responses
of tumors to chemotherapy. Although the pro-apoptotic roles of eugenol and capsaicin have …

Background Metabolomics is a versatile unbiased method to search for biomarkers of
human disease. In particular, one approach in cancer therapy is to promote apoptosis in …

The chemotherapy combined with gene therapy has emerged as a promising strategy for
cancer therapy because of enhanced anticancer efficacy. To this end, we constructed a …