[HTML][HTML] Protective barriers provided by the epidermis

S de Szalay, PW Wertz - International Journal of Molecular Sciences, 2023 - mdpi.com
The skin is the largest organ of the body and consists of an epidermis, dermis and
subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m2 …

[HTML][HTML] Exploring the antimicrobial features of biomaterials for biomedical applications

S Sam, B Joseph, S Thomas - Results in Engineering, 2023 - Elsevier
Biomaterials have revolutionized therapeutic as well as preventive healthcare. This has
given impetus to the development of implants, drug delivery systems, and tissue engineering …

[HTML][HTML] DNA-aptamer-nanographene oxide as a targeted bio-theragnostic system in antimicrobial photodynamic therapy against Porphyromonas gingivalis

M Pourhajibagher, S Etemad-Moghadam… - Scientific Reports, 2022 - nature.com
The aim of this study was to design and evaluate the specificity of a targeted bio-
theragnostic system based on DNA-aptamer-nanographene oxide (NGO) against …

[HTML][HTML] An Update on the Therapeutic Potential of Antimicrobial Peptides against Acinetobacter baumannii Infections

K Rangel, GC Lechuga, DW Provance Jr, CM Morel… - Pharmaceuticals, 2023 - mdpi.com
The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to
global health. The World Health Organization (WHO) has recognized the urgent need to …

[HTML][HTML] In vitro and in vivo antibiofilm activity of the synthetic antimicrobial peptide WLBU2 against multiple drug resistant Pseudomonas aeruginosa strains

S Masihzadeh, M Amin, Z Farshadzadeh - BMC microbiology, 2023 - Springer
Background The global crisis of antibiotic resistance increases the demand for the novel
promising alternative drugs such as antimicrobial peptides (AMPs). Here, the antibiofilm …

[HTML][HTML] In Silico Docking, Resistance Modulation and Biofilm Gene Expression in Multidrug-Resistant Acinetobacter baumannii via Cinnamic and Gallic Acids

NA Abdelaziz, WF Elkhatib, MM Sherif… - Antibiotics, 2022 - mdpi.com
Despite the mounting global burden of antimicrobial resistance (AMR), the generation of
new classes of effective antimicrobials still lags far behind. The interplay between multidrug …

Antimicrobial peptides as antimicrobials for wound care management: a comprehensive review

KA Kanaujia, N Mishra, PS Rajinikanth… - Journal of Drug Delivery …, 2024 - Elsevier
Antimicrobial peptides (AMPs) are low-molecular-weight proteins having a presence in
almost all organisms, from prokaryotes to eukaryotes, and have been a fundamental part of …

[HTML][HTML] Design of a novel analogue peptide with potent antibiofilm activities against Staphylococcus aureus based upon a sapecin B-derived peptide

N Akhash, A Farajzadeh Sheikh, Z Farshadzadeh - Scientific Reports, 2024 - nature.com
Nowadays, antimicrobial peptides are promising to confront the existing global crisis of
antibiotic resistance. Here, a novel analogue peptide (mKLK) was designed based upon a D …

[HTML][HTML] Recent developments in detection and therapeutic approaches for antibiotic-resistant bacterial infections

K Moorthy, KC Chang, HH Yang, WM Su… - Journal of Food and …, 2023 - ncbi.nlm.nih.gov
Owing to the widespread emergence and proliferation of antibiotic-resistant bacteria, the
therapeutic benefits of antibiotics have been reduced. In addition, the ongoing evolution of …

Pyrogallol loaded chitosan-based polymeric hydrogel for controlling Acinetobacter baumannii wound infections: Synthesis, characterization, and topical application

G Abirami, R Alexpandi, E Jayaprakash… - International Journal of …, 2024 - Elsevier
Antibacterial hydrogels have emerged as a promising approach for wound healing, owing to
their ability to integrate antibacterial agents into the hydrogel matrix. Benefiting from its …