As more bioactivity and protein structure data become available, scoring functions (SFs)
using machine learning (ML) to leverage these data sets continue to gain further accuracy …

Infectious diseases are an enormous public health burden and a growing threat to human
health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant …

In this paper, we have reported the synthesis of some coumarin-benzothiazole based azo
dyes (C 1-C 5). The structure of the synthesised dyes was precisely established from their …

Today, tuberculosis (TB) caused by the acid-fast bacilli, Mycobacterium tuberculosis (Mtb) is
the most infectious killer disease globally with high morbidity and mortality rates. The rapid …

Summary Bacille Calmette-Guerin (BCG) is the only licensed vaccine against
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) disease …

The quinoline moiety remains a privileged antitubercular (anti‐TB) pharmacophore,
whereas 8‐nitrobenzothiazinones are emerging potent antimycobacterial agents with two …

Nitrobenzothiazinones (BTZs) are a very potent class of antibiotics against Mycobacterium
tuberculosis. However, relationships between their structural properties and whole cell …

Based on extensive experimental studies, a huge number of phytochemicals showed
potential activity against tuberculosis (TB) at a lower minimum inhibitory concentration (MIC) …

The cell wall of Mycobacterium tuberculosis and related organisms has a very complex and
unusual organization that makes it much less permeable to nutrients and antibiotics, leading …

In our continued efforts to find potential chemotherapeutics active against drug-resistant
(DR) Mycobacterium tuberculosis (Mtb), causative agent of Tuberculosis (TB) and to curb the …