Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
[HTML][HTML] Copper in cancer: from pathogenesis to therapy
D Guan, L Zhao, X Shi, X Ma, Z Chen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
One of the basic trace elements for the structure and metabolism of human tissue is copper.
However, as a heavy metal, excessive intake or abnormal accumulation of copper in the …
However, as a heavy metal, excessive intake or abnormal accumulation of copper in the …
Extracellular matrix regulation in physiology and in brain disease
A Soles, A Selimovic, K Sbrocco, F Ghannoum… - International journal of …, 2023 - mdpi.com
The extracellular matrix (ECM) surrounds cells in the brain, providing structural and
functional support. Emerging studies demonstrate that the ECM plays important roles during …
functional support. Emerging studies demonstrate that the ECM plays important roles during …
Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies
Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
[HTML][HTML] Ca & Mn dual-ion hybrid nanostimulator boosting anti-tumor immunity via ferroptosis and innate immunity awakening
X Deng, T Liu, Y Zhu, J Chen, Z Song, Z Shi, H Chen - Bioactive Materials, 2024 - Elsevier
Limited by low tumor immunogenicity and the immunosuppressive tumor microenvironment
(TME), triple-negative breast cancer (TNBC) has been poorly responsive to immunotherapy …
(TME), triple-negative breast cancer (TNBC) has been poorly responsive to immunotherapy …
Covalent organic framework nanoparticles: Overcoming the challenges of hypoxia in cancer therapy
Hypoxia, or low oxygen levels, is a common feature of the tumor microenvironment. It is
caused by the aggressive proliferation of cancer cells, which consume more oxygen than …
caused by the aggressive proliferation of cancer cells, which consume more oxygen than …
Cancer Stem‐Like Cells‐Oriented Surface Self‐Assembly to Conquer Radioresistance
Q Wang, H Cao, X Hou, D Wang, Z Wang… - Advanced …, 2023 - Wiley Online Library
Cancer stem‐like cells (CSCs), capable of indefinite self‐renewal and differentiation, are
considered to be the root cause of tumor radiotherapy (RT) resistance. However, the CSCs …
considered to be the root cause of tumor radiotherapy (RT) resistance. However, the CSCs …
Role of oxidative stress in metabolic reprogramming of brain cancer
Simple Summary According to Globocan 2020 data, approximately 308,102 new cases of
brain cancer and central nervous system (CNS) cancers were reported worldwide, with …
brain cancer and central nervous system (CNS) cancers were reported worldwide, with …
Lactylation stabilizes DCBLD1 activating the pentose phosphate pathway to promote cervical cancer progression
Q Meng, H Sun, Y Zhang, X Yang, S Hao, B Liu… - Journal of Experimental …, 2024 - Springer
Abstract Background Discoidin, CUB, and LCCL domain-containing type I (DCBLD1) is
identified as an oncogene involved in multiple regulation of tumor progression, but specific …
identified as an oncogene involved in multiple regulation of tumor progression, but specific …
Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
Glioblastoma (GBM) is a hypoxic and" immune-cold" tumor containing rich stromal signaling
molecules and cell populations, such as proteases and immunosuppressive tumor …
molecules and cell populations, such as proteases and immunosuppressive tumor …