Osteoarthritis (OA) is the most prevalent joint disease in older people and is characterized
by the progressive destruction of articular cartilage, synovial inflammation, changes in …

Abnormal levels of reactive oxygen species (ROS) and inflammatory cytokines have been
observed in the skeletal muscle during muscle wasting including sarcopenia. However, the …

Recent evidence has revealed the importance of reciprocal functional interactions between
different types of mononuclear cells in coordinating the repair of injured muscles. In …

Biological aging is associated with progressive damage accumulation, loss of organ
reserves, and systemic inflammation ('inflammaging'), which predispose for a wide spectrum …

The present study aimed to assess the association between sedentary behavior and
sarcopenia among adults aged≥ 65 years. Cross-sectional data from the Study on Global …

A decline in mitochondrial biogenesis and mitochondrial protein quality control in skeletal
muscle is a common finding in aging, but exercise training has been suggested as a …

Aging is associated with alterations in glucose metabolism and sarcopenia that jointly
contribute to a higher risk of developing type 2 diabetes. Because aging is considered as a …

Regular physical activity seems to be one of the most important contributors to prevent
disease and promote health. Being physically active reduces the risk of developing chronic …

Chronic inflammation in aging is characterized by increased inflammatory cytokines, bone
loss, decreased adaptation, and defective tissue repair in response to injury. Aging leads to …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …