Resistance mechanisms to anti-angiogenic therapies in cancer

Y Haibe, M Kreidieh, H El Hajj, I Khalifeh… - Frontiers in …, 2020 - frontiersin.org
Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth …

Vascular endothelial growth factor family of ligands and receptors

ZK Otrock, JA Makarem, AI Shamseddine - Blood Cells, Molecules, and …, 2007 - Elsevier
VEGF signaling often represents a critical rate-limiting step in physiological angiogenesis.
The VEGF family comprises seven secreted glycoproteins that are designated VEGF-A …

Prognostic significance of vascular endothelial cell growth factors-A,-C and-D in breast cancer and their relationship with angio-and lymphangiogenesis

RAA Mohammed, A Green, S El-Shikh, EC Paish… - British journal of …, 2007 - nature.com
Vascular endothelial cell growth factors (VEGF)-A,-C and-D have potent angio and
lymphangiogenic functions in experimental models, although their role in the progression of …

CT-guided survival prediction of esophageal cancer

Z Lin, W Cai, W Hou, Y Chen, B Gao… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Survival prediction of esophageal cancer is an essential task for doctors to make
personalized cancer treatment plans. However, handcrafted features from medical images …

Prognostic value of vascular endothelial growth factor expression in patients with esophageal cancer: a systematic review and meta-analysis

M Chen, E Cai, J Huang, P Yu, K Li - Cancer epidemiology, biomarkers & …, 2012 - AACR
Background: VEGF is a prime mediator of tumorigenesis and metastasis. Various studies
assessing the prognostic value of VEGF in patients with esophageal cancer remain …

Clinical and prognostic significance of OPN and VEGF expression in patients with non-small-cell lung cancer

Q Lin, L Guo, G Lin, Z Chen, T Chen, J Lin, B Zhang… - Cancer …, 2015 - Elsevier
Background Osteopontin (OPN) and vascular endothelial growth factor (VEGF) play
important roles in cancer progression and angiogenesis. In the current study we aimed to …

[HTML][HTML] Downregulation of miR-375 contributes to ERBB2-mediated VEGFA overexpression in esophageal cancer

S Ren, X Tan, MZ Fu, S Ren, X Wu, T Chen… - Journal of …, 2021 - ncbi.nlm.nih.gov
Esophageal cancer (EC) is a lethal cancer with an extremely aggressive nature and poor
survival rate. However, the molecular mechanisms driving the occurrence and progression …

Molecular prognostic factors in adenocarcinoma of the esophagus and gastroesophageal junction

SM Lagarde, FJW ten Kate, DJ Richel… - Annals of surgical …, 2007 - Springer
Objective This review describes genetic and molecular changes related to adenocarcinoma
of the esophagus and gastroesophageal junction (GEJ) with emphasis on prognostic value …

Linking circulating serum proteins with clinical outcomes in esophageal adenocarcinoma—an emerging role for chemokines

NE Donlon, A Sheppard, M Davern, F O'Connell… - Cancers, 2020 - mdpi.com
Simple Summary Cancer of the esophagus (food pipe) is an aggressive type of cancer with
poor prognosis and rates are increasing. Current treatments help to prolong survival but only …

High expressions of galectin-1 and VEGF are associated with poor prognosis in gastric cancer patients

J Chen, D Tang, S Wang, QG Li, JR Zhang, P Li, Q Lu… - Tumor Biology, 2014 - Springer
High expressions of galectin-1 and vascular endothelial growth factor (VEGF) are correlated
with biological behavior in some cancers. The aim of this study is to evaluate the …