[HTML][HTML] Reprogramming of Treg cells in the inflammatory microenvironment during immunotherapy: a literature review

X Wu, Z Zhou, Q Cao, Y Chen, J Gong… - Frontiers in …, 2023 - frontiersin.org
Regulatory T cells (Treg), as members of CD4+ T cells, have garnered extensive attention in
the research of tumor progression. Treg cells have the function of inhibiting the immune …

Advances in HPV‐associated tumor management: Therapeutic strategies and emerging insights

X Gong, H Chi, Z Xia, G Yang… - Journal of Medical …, 2023 - Wiley Online Library
With the rapid increase in the incidence of cervical cancer, anal cancer and other cancers,
human papillomavirus (HPV) infection has become a growing concern. Persistent infection …

[HTML][HTML] Integrating multiple machine learning methods to construct glutamine metabolism-related signatures in lung adenocarcinoma

P Zhang, S Pei, L Wu, Z Xia, Q Wang… - Frontiers in …, 2023 - frontiersin.org
Background Glutamine metabolism (GM) is known to play a critical role in cancer
development, including in lung adenocarcinoma (LUAD), although the exact contribution of …

[HTML][HTML] Innovative breakthroughs facilitated by single-cell multi-omics: manipulating natural killer cell functionality correlates with a novel subcategory of melanoma …

Z Zhao, Y Ding, LJ Tran, G Chai, L Lin - Frontiers in immunology, 2023 - frontiersin.org
Background Melanoma is typically regarded as the most dangerous form of skin cancer.
Although surgical removal of in situ lesions can be used to effectively treat metastatic …

[HTML][HTML] FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC

H Chi, X Gao, Z Xia, W Yu, X Yin, Y Pan… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Endometrial cancer (UCEC) is a highly heterogeneous gynecologic
malignancy that exhibits variable prognostic outcomes and responses to immunotherapy …

[HTML][HTML] A novel signature predicts prognosis and immunotherapy in lung adenocarcinoma based on cancer-associated fibroblasts

Q Ren, P Zhang, H Lin, Y Feng, H Chi… - Frontiers in …, 2023 - frontiersin.org
Background Extensive research has established the significant correlations between cancer-
associated fibroblasts (CAFs) and various stages of cancer development, including initiation …

[HTML][HTML] Proposing new early detection indicators for pancreatic cancer: Combining machine learning and neural networks for serum miRNA-based diagnostic model

H Chi, H Chen, R Wang, J Zhang, L Jiang… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background Pancreatic cancer (PC) is a lethal malignancy that ranks seventh in terms of
global cancer-related mortality. Despite advancements in treatment, the five-year survival …

[HTML][HTML] Integrated multi-omics identified the novel intratumor microbiome-derived subtypes and signature to predict the outcome, tumor microenvironment …

B Zhang, J Liu, H Li, B Huang, B Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: The extremely malignant tumour known as pancreatic cancer (PC) lacks
efficient prognostic markers and treatment strategies. The microbiome is crucial to how …

[HTML][HTML] Integrated single-cell and bulk RNA sequencing revealed the molecular characteristics and prognostic roles of neutrophils in pancreatic cancer

B Zhang, J Sun, H Guan, H Guo, B Huang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Pancreatic cancer, one of the most prevalent tumors of the digestive system, has a dismal
prognosis. Cancer of the pancreas is distinguished by an inflammatory tumor …

[HTML][HTML] Revealing the role of regulatory T cells in the tumor microenvironment of lung adenocarcinoma: a novel prognostic and immunotherapeutic signature

P Zhang, X Zhang, Y Cui, Z Gong, W Wang… - Frontiers in …, 2023 - frontiersin.org
Background Regulatory T cells (Tregs), are a key class of cell types in the immune system. In
the tumor microenvironment (TME), the presence of Tregs has important implications for …