Nanoparticle-mediated combination therapy: two-in-one approach for cancer

S Gurunathan, MH Kang, M Qasim, JH Kim - International journal of …, 2018 - mdpi.com
Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

[HTML][HTML] Biomacromolecules as carriers in drug delivery and tissue engineering

Y Zhang, T Sun, C Jiang - Acta Pharmaceutica Sinica B, 2018 - Elsevier
Natural biomacromolecules have attracted increased attention as carriers in biomedicine in
recent years because of their inherent biochemical and biophysical properties including …

Recent developments in natural biopolymer based drug delivery systems

T Fazal, BN Murtaza, M Shah, S Iqbal, M Rehman… - RSC …, 2023 - pubs.rsc.org
Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …

Mitochondria and nuclei dual-targeted heterogeneous hydroxyapatite nanoparticles for enhancing therapeutic efficacy of doxorubicin

H Xiong, S Du, J Ni, J Zhou, J Yao - Biomaterials, 2016 - Elsevier
Dual-targeted nanoparticles have been increasingly used to realize greater anti-proliferation
effect by attacking double key sites of tumor cells. In order to retain nuclei inhibition effect …

Carbohydrate-based amphiphilic nano delivery systems for cancer therapy

K Liu, X Jiang, P Hunziker - Nanoscale, 2016 - pubs.rsc.org
Nanoparticles (NPs) are novel drug delivery systems that have been attracting more and
more attention in recent years, and have been used for the treatment of cancer, infection …

[HTML][HTML] Current trends in ATRA delivery for cancer therapy

MV Giuli, PN Hanieh, E Giuliani, F Rinaldi… - Pharmaceutics, 2020 - mdpi.com
All-Trans Retinoic Acid (ATRA) is the most active metabolite of vitamin A. It is critically
involved in the regulation of multiple processes, such as cell differentiation and apoptosis …

Carotenoids in cancer metastasis—Status quo and outlook

L Koklesova, A Liskova, M Samec, K Zhai, M Abotaleb… - Biomolecules, 2020 - mdpi.com
Metastasis represents a major obstacle in cancer treatment and the leading cause of cancer-
related deaths. Therefore, the identification of compounds targeting the multi-step and …

Amphiphilic polysaccharides as building blocks for self-assembled nanosystems: molecular design and application in cancer and inflammatory diseases

X Yang, X Shi, R D'arcy, N Tirelli, G Zhai - Journal of Controlled Release, 2018 - Elsevier
Polysaccharides (PSs) have been extensively studied in healthcare applications; here, we
focus our attention on their use as components of nanomaterials in the management of …

Multiple-therapy strategies via polysaccharides-based nano-systems in fighting cancer

M Li, Y Zhao, W Zhang, S Zhang, S Zhang - Carbohydrate Polymers, 2021 - Elsevier
Polysaccharide-based biomaterials (eg, chitosan, dextran, hyaluronic acid, chondroitin
sulfate and heparin) have received great attention in healthcare, particularly in drug delivery …

Attempts to strengthen and simplify the tumor vascular normalization strategy using tumor vessel normalization promoting nanomedicines

S Du, H Xiong, C Xu, Y Lu, J Yao - Biomaterials science, 2019 - pubs.rsc.org
Tumor vascular normalization theory opened the door for the rational use of antiangiogenic
agents and chemotherapeutics. However, efforts to seize the normalization window have …