Human Molecular Genetics Review Issue 2022

F Cheng, D Geschwind - Human Molecular Genetics, 2022 - academic.oup.com
Recent remarkable advances in high-throughput genotyping and next-generation DNA-
sequencing technologies have generated massive human genome sequencing datasets …

Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

MC Pahl, P Sharma, RM Thomas, Z Thompson… - bioRxiv, 2023 - biorxiv.org
Genome-wide association studies (GWAS) have identified hundreds of genetic signals
associated with autoimmune disease. The majority of these signals are located in non …

Trans-Ancestry Analysis of Psychosis Biotypes: Shared Polygenic Risk and Unique Genomic Associations

E Gershon, C Xia, N Alliey-Rodriguez, C Tamminga… - 2024 - researchsquare.com
Abstract The Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP) has
categorized psychosis disorders (Schizophrenia, Schizoaffective Disorder and Bipolar …