Postpartum depression: Etiology, treatment and consequences for maternal care

S Brummelte, LAM Galea - Hormones and behavior, 2016 - Elsevier
This article is part of a Special Issue “Parental Care”. Pregnancy and postpartum are
associated with dramatic alterations in steroid and peptide hormones which alter the …

Cytokine and growth factor activation in vivo and in vitro after spinal cord injury

E Garcia, J Aguilar-Cevallos… - Mediators of …, 2016 - Wiley Online Library
Spinal cord injury results in a life‐disrupting series of deleterious interconnected
mechanisms encompassed by the primary and secondary injury. These events are mediated …

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction

M Orre, W Kamphuis, LM Osborn, AHP Jansen… - Neurobiology of …, 2014 - Elsevier
Reactive astrocytes and microglia are associated with amyloid plaques in Alzheimer's
disease (AD). Yet, not much is known about the molecular alterations underlying this …

Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function

S Hosseini, E Wilk, K Michaelsen-Preusse… - Journal of …, 2018 - Soc Neuroscience
Acute influenza infection has been reported to be associated with neurological symptoms.
However, the long-term consequences of an infection with neurotropic and non-neurotropic …

Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits

Z Xu, N Xiao, Y Chen, H Huang, C Marshall… - Molecular …, 2015 - Springer
Background Preventing or reducing amyloid-beta (Aβ) accumulation in the brain is an
important therapeutic strategy for Alzheimer's disease (AD). Recent studies showed that the …

AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav1.6‐Mediated Astrocyte Autophagy

DD Zhu, YL Huang, SY Guo, N Li, XW Yang… - Advanced …, 2023 - Wiley Online Library
The pathology of sepsis‐associated encephalopathy (SAE) is related to astrocyte‐
inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects …

Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load

V Calsolaro, PM Matthews, CK Donat… - Molecular …, 2021 - nature.com
Abstract 11C-BU99008 is a novel positron emission tomography (PET) tracer that enables
selective imaging of astrocyte reactivity in vivo. To explore astrocyte reactivity associated …

Alzheimer's disease: a journey from amyloid peptides and oxidative stress, to biomarker technologies and disease prevention strategies—gains from AIBL and DIAN …

RN Martins, V Villemagne, HR Sohrabi… - Journal of …, 2018 - content.iospress.com
Worldwide there are over 46 million people living with dementia, and this number is
expected to double every 20 years reaching about 131 million by 2050. The cost to the …

Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden

SR Rainey-Smith, GN Mazzucchelli… - Translational …, 2018 - nature.com
The glymphatic system is postulated to be a mechanism of brain Aβ-amyloid clearance and
to be most effective during sleep. Ablation of the astrocytic end-feet expressed water …

Astroglia as a cellular target for neuroprotection and treatment of neuro‐psychiatric disorders

B Liu, AG Teschemacher, S Kasparov - Glia, 2017 - Wiley Online Library
Astrocytes are key homeostatic cells of the central nervous system. They cooperate with
neurons at several levels, including ion and water homeostasis, chemical signal …