Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
SP Kalra, MG Dube, S Pu, B Xu, TL Horvath… - Endocrine …, 1999 - academic.oup.com
THE PAST decade has witnessed an upsurge in our understanding of the hypothalamic
regulation of appetite. Expression of appetite or the motivational drive toward an energy …
regulation of appetite. Expression of appetite or the motivational drive toward an energy …
Hypocretin/orexin‐and melanin‐concentrating hormone‐expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide …
C Broberger, L De Lecea, JG Sutcliffe… - Journal of …, 1998 - Wiley Online Library
Cells in the lateral hypothalamus and in the arcuate nucleus play prominent roles in the
central control of food intake; however, a neurochemical link connecting these potential …
central control of food intake; however, a neurochemical link connecting these potential …
Behavioral characterization of neuropeptide Y knockout mice
AW Bannon, J Seda, M Carmouche, JM Francis… - Brain research, 2000 - Elsevier
An extensive behavioral characterization was conducted with mice lacking the gene for
neuropeptide Y (NPY) including response to 24 and 48 h fast and challenge with small …
neuropeptide Y (NPY) including response to 24 and 48 h fast and challenge with small …
Characterization of neuropeptide Y, Y2 receptor knockout mice in two animal models of learning and memory processing
JP Redrobe, Y Dumont, H Herzog, R Quirion - Journal of Molecular …, 2004 - Springer
Neuropeptide Y (NPY) and, in particular, the Y 2 receptor subtype, has been suggested to
be involved in learning and memory processing. However, the precise role of Y 2 receptors …
be involved in learning and memory processing. However, the precise role of Y 2 receptors …
Emerging functions of neuropeptide Y Y2 receptors in the brain
T Kaga, M Fujimiya, A Inui - Peptides, 2001 - Elsevier
The Y2 receptor is the predominant neuropeptide Y (NPY) receptor subtype in the brain. Y2
receptor mRNA is discretely distributed in the brain, including specific subregions of the …
receptor mRNA is discretely distributed in the brain, including specific subregions of the …
Neural substrates for leptin and neuropeptide Y (NPY) interaction: hypothalamic sites associated with inhibition of NPY-induced food intake
M Yokosuka, B Xu, S Pu, PS Kalra, SP Kalra - Physiology & behavior, 1998 - Elsevier
YOKOSUKA M., B. XU, S. PU, PS KALRA AND SP KALRA. Neural Substrates for Leptin and
NPY Interaction: Hypothalamic Sites Associated with Inhibition of NPY-Induced Food Intake …
NPY Interaction: Hypothalamic Sites Associated with Inhibition of NPY-Induced Food Intake …
Inhibition of neuropeptide Y (NPY)-induced feeding and c-Fos response in magnocellular paraventricular nucleus by a NPY receptor antagonist: a site of NPY action
M Yokosuka, PS Kalra, SP Kalra - Endocrinology, 1999 - academic.oup.com
Neuropeptide Y (NPY) is one of the important endogenous orexigenic peptides. In these
studies we employed c-Fos immunostaining and a selective NPY Y1 receptor antagonist to …
studies we employed c-Fos immunostaining and a selective NPY Y1 receptor antagonist to …
Increased appetite augments hypothalamic NPY Y1 receptor gene expression: effects of anorexigenic ciliary neurotropic factor
B Xu, PS Kalra, LL Moldawer, SP Kalra - Regulatory peptides, 1998 - Elsevier
Neuropeptide Y (NPY) is a potent endogenous appetite transducer but the NPY receptor
subtype mediating the induction of appetite is unknown. Evaluation of hypothalamic NPY Y1 …
subtype mediating the induction of appetite is unknown. Evaluation of hypothalamic NPY Y1 …
Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIBO3304 (Y1) and CGP71683A (Y5)
Y Dumont, A Cadieux, H Doods… - Canadian journal of …, 2000 - cdnsciencepub.com
We have evaluated 3 newly developed neuropeptide Y receptor antagonists in various in
vitro binding and bioassays: BIBO3304 (Y1), T4 [NPY33-36] 4 (Y2), and CGP71683A (Y5). In …
vitro binding and bioassays: BIBO3304 (Y1), T4 [NPY33-36] 4 (Y2), and CGP71683A (Y5). In …
Appetite suppression based on selective inhibition of NPY receptors
S Chamorro, O Della-Zuana, JL Fauchere… - International journal of …, 2002 - nature.com
AIM: The aim of this review is to critically assess available evidence that blockade of the
actions of NPY at one of the five NPY receptor subtypes represents an attractive new drug …
actions of NPY at one of the five NPY receptor subtypes represents an attractive new drug …