Summary Since 1989, 18 second-generation antiseizure medications have reached the
market, resulting in a greatly increased range of treatment options for patients and …

Objective Emotional dysregulation and irritability are common in individuals with autism
spectrum disorder (ASD). We conducted the first meta-analysis assessing the efficacy of a …

Glutamate is the brain's main excitatory neurotransmitter. Glutamatergic neurons primarily
compose basic neuronal networks, especially in the cortex. An imbalance of excitatory and …

PURPOSE OF REVIEW The treatment of epilepsy in children is highly individualized at each
and every major step in the management. This review examines various factors that modify …

Water pollution is one of the biggest problems in world today, which is directly related to the
progress and development of the countries. Using the adsorbents of porous nanostructures …

The cellular, molecular, and metabolic mechanisms that underlie the development of mesial
temporal lobe epilepsy are incompletely understood. Here we review the role of astrocytes …

To guide health care professionals in Belgium in selecting the appropriate antiepileptic
drugs (AEDs) for their epilepsy patients, a group of Belgian epilepsy experts developed …

Impairments of the dialog between excitation and inhibition (E/I) is commonly associated to
neuropsychiatric disorders like autism, bipolar disorders and epilepsy. Moderate levels of …

Aim To compare and rank the efficacy and safety of antiseizure medication (ASM) in patients
with Lennox–Gastaut syndrome (LGS). Method We included randomized controlled trials …

Background Refractory status epilepticus (RSE) represents a serious medical condition
requiring early and targeted therapy. Given the increasing number of elderly or multimorbid …