Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …

Liver fibrosis is a life-threatening disease, with challenging morbidity and mortality for
healthcare systems worldwide. It imparts an enormous economic burden to societies …

Backgroud Schisandra chinensis, a traditional Chinese medicine for liver protection, can
significantly improve liver fibrosis. However, it is still unclear which active components in …

Background G-protein coupled receptors (GPCRs) are recognized as attractive targets for
drug therapy. However, it remains poorly understood how GPCRs, except for a few …

Hepatic fibrosis (HF) refers to the pathophysiological process of connective tissue dysplasia
in the liver caused by various pathogenic factors. Nowadays, HF is becoming a severe threat …

Liver fibrosis is the result of a chronic pathological condition caused by the activation of
hepatic stellate cells (HSCs), which induces the excessive deposition of extracellular matrix …

Aims This study aimed to elucidate the role of Interleukin-11 (IL-11) in hepatic fibrosis (HF)
and its potential as a therapeutic target for HF treatment. Materials and methods We …

Sinapic acid (SA) is a natural pharmacological active compound found in berries, nuts, and
cereals. The current study aimed to investigate the protective effects of SA against …

Liver fibrosis of different etiologies is a serious health problem worldwide. There is no
effective therapy available for liver fibrosis except the removal of the underlying cause of …

Liver fibrosis is a common link in the transformation of acute and chronic liver diseases to
cirrhosis. It is of great clinical significance to study the factors associated with the induction of …