Bronchial asthma is a chronic inflammatory disease of the respiratory tract that varies in
terms of clinical presentations (phenotypes) and distinct underlying pathophysiological …

OBJECTIVE: To determine the relationship between allelic variations in genes involved in
fluticasone propionate (FP) metabolism and asthma control among children with asthma …

Long-acting β 2-agonists (LABAs) have been shown to be effective first-line bronchodilators
in the treatment of COPD patients, and inhaled corticosteroids (ICSs) have been shown to …

Vascular endothelial growth factor (VEGF), a cytokine expressed in the respiratory epithelial
cells, induces vascular hyperpermeability and edema, symptoms that are alleviated by …

The aim of this study was to compare the efficacy and safety of salmeterol/fluticasone
propionate combination product (SFC) with fluticasone propionate (FP) plus oral …

Lipids and their mediators are known to play a pro-inflammatory role in several human
diseases including asthma. The influence of leukotrienes and prostaglandins through …

Objectives The impact of inhaled corticosteroids (ICS) on eosinophilic inflammation in
asthma is well established, but their effect in a real-life setting has not been extensively …

Background: Asthma is a major public health problem worldwide, and the morbidity and
mortality of asthma have increased in the past two decades. The reputed efficacy, low cost …

In asthma, inflammatory mediators that are released in the airways by recruited inflammatory
cells and by resident structural cells result in airway hyperresponsiveness caused by …

Background International guidelines advocate using daily inhaled corticosteroids (ICS) in
the management of children and adults with persistent asthma. However, in real world …