Merkel Cell Carcinoma (MCC) is a rare but highly aggressive form of non–melanoma skin
cancer whose 5-year survival rate is 63%. Merkel cell polyomavirus (MCPyV), a small DNA …

Background: Non-melanoma skin cancer (NMSC) stands as an umbrella term for common
cutaneous malignancies, including basal cell carcinoma (BCC) and cutaneous squamous …

Background Merkel cell carcinoma is among the most aggressive and lethal of primary skin
cancers, with a high rate of distant metastasis. Anti-programmed death receptor 1 (anti-PD …

Background Merkel cell carcinoma (MCC) is an immunogenic but aggressive skin cancer.
Even after complete resection and radiation, relapse rates are high. PD-1 and PD-L1 …

The NCCN Guidelines for Merkel Cell Carcinoma (MCC) provide recommendations for
diagnostic workup, clinical stage, and treatment options for patients. The panel meets …

Merkel cell carcinoma is a rare neuroendocrine carcinoma that typically appears in sun‐
exposed areas of the elderly. It has a poor prognosis and with its incidence projected to …

Treating immunosuppressive tumors represents a major challenge in cancer therapies.
Activation of STING signaling has shown remarkable potential to invigorate the …

Purpose We aimed to determine whether the pan-immune-inflammation value (PIV) of
patients with Merkel cell carcinoma (MCC) at primary diagnosis differs from controls and …

Merkel cell carcinoma (MCC) is a highly immunogenic skin cancer primarily induced by
Merkel cell polyomavirus, which is driven by the expression of the oncogenic T antigens (T …

Myeloid derived suppressor cells (MDSCs) are a heterogenous population of myeloid cells
derived from monocyte and granulocyte precursors. They are pathologically expanded in …