Compromised microvascular oxygen delivery increases brain tissue vulnerability with age

M Moeini, X Lu, PK Avti, R Damseh, S Bélanger… - Scientific reports, 2018 - nature.com
Despite the possible role of impaired cerebral tissue oxygenation in age-related cognition
decline, much is still unknown about the changes in brain tissue pO2 with age. Using a …

Comparison of principal and independent component analysis in removing extracerebral interference from near-infrared spectroscopy signals

J Virtanen, T Noponen… - Journal of biomedical …, 2009 - spiedigitallibrary.org
Near-infrared spectroscopy (NIRS) is a method for noninvasive estimation of cerebral
hemodynamic changes. Principal component analysis (PCA) and independent component …

Tissue oxygenation in brain, muscle, and fat in a rat model of sleep apnea: differential effect of obstructive apneas and intermittent hypoxia

I Almendros, R Farré, AM Planas, M Torres… - Sleep, 2011 - academic.oup.com
Abstract Study Objectives: To test the hypotheses that the dynamic changes in brain oxygen
partial pressure (PtO2) in response to obstructive apneas or to intermittent hypoxia differ …

Therapeutic hypercapnia improves functional recovery and attenuates injury via antiapoptotic mechanisms in a rat focal cerebral ischemia/reperfusion model

T Tao, Y Liu, J Zhang, Y Xu, W Li, M Zhao - Brain research, 2013 - Elsevier
Recent studies have demonstrated neuroprotective effects of therapeutic hypercapnia for
different forms of brain injury. However, few studies have assessed the neuroprotective and …

Absolute measurement of cerebral optical coefficients, hemoglobin concentration and oxygen saturation in old and young adults with near-infrared spectroscopy

B Hallacoglu, A Sassaroli, M Wysocki… - … of biomedical optics, 2012 - spiedigitallibrary.org
We present near-infrared spectroscopy measurement of absolute cerebral hemoglobin
concentration and saturation in a large sample of 36 healthy elderly (mean age, 85±6 years) …

Hypercapnia-induced cerebral hyperperfusion: an underrecognized clinical entity

JM Pollock, AR Deibler, CT Whitlow… - American journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The incidence of cerebral hyperperfusion and
hypoperfusion, respectively, resulting from hypercapnia and hypocapnia in hospitalized …

Contribution of NIRS to the study of prefrontal cortex for verbal fluency in aging

K Kahlaoui, G Di Sante, J Barbeau, M Maheux… - Brain and language, 2012 - Elsevier
Healthy aging is characterized by a number of changes on brain structure and function.
Several neuroimaging studies have shown an age-related reduction in hemispheric …

Practical steps for applying a new dynamic model to near-infrared spectroscopy measurements of hemodynamic oscillations and transient changes: implications for …

JM Kainerstorfer, A Sassaroli, B Hallacoglu… - Academic radiology, 2014 - Elsevier
Rationale and Objectives Perturbations in cerebral blood volume (CBV), blood flow (CBF),
and metabolic rate of oxygen (CMRO 2) lead to associated changes in tissue concentrations …

Cerebral time domain-NIRS: reproducibility analysis, optical properties, hemoglobin species and tissue oxygen saturation in a cohort of adult subjects

G Giacalone, M Zanoletti, D Contini, R Re… - Biomedical optics …, 2017 - opg.optica.org
The reproducibility of cerebral time-domain near-infrared spectroscopy (TD-NIRS) has not
been investigated so far. Besides, reference intervals of cerebral optical properties, of …

Reduced haemodynamic response in the ageing visual cortex measured by absolute fNIRS

LMK Ward, RT Aitchison, M Tawse, AJ Simmers… - Plos one, 2015 - journals.plos.org
The effect of healthy ageing on visual cortical activation is still to be fully explored. This study
aimed to elucidate whether the haemodynamic response (HDR) of the visual cortex altered …