Degenerative cervical myelopathy—update and future directions

JH Badhiwala, CS Ahuja, MA Akbar, CD Witiw… - Nature Reviews …, 2020 - nature.com
Degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction in
adults worldwide. DCM encompasses various acquired (age-related) and congenital …

Treatment of spinal cord injury with mesenchymal stem cells

LL Liau, QH Looi, WC Chia, T Subramaniam, MH Ng… - Cell & bioscience, 2020 - Springer
Background Spinal cord injury (SCI) is the damage to the spinal cord that can lead to
temporary or permanent loss of function due to injury to the nerve. The SCI patients are often …

Epidemiology of traumatic spinal cord injury: a large population-based study

C Barbiellini Amidei, L Salmaso, S Bellio, M Saia - Spinal Cord, 2022 - nature.com
Study design A retrospective population-based study. Objectives Describe the incidence of
traumatic spinal cord injury (TSCI) and mortality risks, based on the characteristics of the …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

E Nichols, CEI Szoeke, SE Vollset, N Abbasi… - The Lancet …, 2019 - thelancet.com
Background The number of individuals living with dementia is increasing, negatively
affecting families, communities, and health-care systems around the world. A successful …

Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

SL James, A Theadom, RG Ellenbogen… - The Lancet …, 2019 - thelancet.com
Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly
recognised as global health priorities in view of the preventability of most injuries and the …

Traumatic spinal cord injury—repair and regeneration

CS Ahuja, S Nori, L Tetreault, J Wilson, B Kwon… - …, 2017 - journals.lww.com
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …

Traumatic spinal cord injury

CS Ahuja, JR Wilson, S Nori, M Kotter… - Nature reviews Disease …, 2017 - nature.com
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …

CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling

S Xu, J Wang, J Zhong, M Shao, J Jiang… - Clinical and …, 2021 - Wiley Online Library
Background Neuroinflammation‐induced secondary injury is an important cause of
sustained progression of spinal cord injury. Inflammatory programmed cell death pyroptosis …

Degenerative cervical myelopathy: epidemiology, genetics, and pathogenesis

A Nouri, L Tetreault, A Singh, SK Karadimas… - Spine, 2015 - journals.lww.com
Study Design. Review. Objective. To formally introduce “degenerative cervical
myelopathy”(DCM) as the overarching term to describe the various degenerative conditions …