Ginsenoside Rg1 in neurological diseases: From bench to bedside

S Yang, J Wang, P Cheng, L Chen, J Hu… - Acta Pharmacologica …, 2023 - nature.com
Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Prevalence and mechanisms of skeletal muscle atrophy in metabolic conditions

L Jun, M Robinson, T Geetha, TL Broderick… - International Journal of …, 2023 - mdpi.com
Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …

Disentangling mitochondria in Alzheimer's disease

A Johri - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

Physical Exercise as Disease-Modifying Alternative against Alzheimer's Disease: A Gut–Muscle–Brain Partnership

D Cutuli, D Decandia, G Giacovazzo… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a common cause of dementia characterized by
neurodegenerative dysregulations, cognitive impairments, and neuropsychiatric symptoms …

Exercise modifies the transcriptional regulatory features of monocytes in alzheimer's patients: A multi-omics integration analysis based on single cell technology

Y Chen, Y Sun, Z Luo, X Chen, Y Wang, B Qi… - Frontiers in Aging …, 2022 - frontiersin.org
Monocytes have been reported to be important mediators of the protective effect of exercise
against the development of Alzheimer's disease (AD). This study aims explored the …

Modulation of Inflammatory Mediators and Microglial Activation Through Physical Exercise in Alzheimer's and Parkinson's Diseases

EJR de Almeida, HJ Ibrahim… - Neurochemical …, 2022 - Springer
Neuroinflammation is an inflammatory process in the central nervous system (CNS), in
addition to being one of the main features of Alzheimer's disease (AD) and Parkinson's …

Digging into the intrinsic Capacity Concept: can it be Applied to Alzheimer's Disease?

S López-Ortiz, G Caruso, E Emanuele… - Progress in …, 2024 - Elsevier
Historically, aging research has largely centered on disease pathology rather than
promoting healthy aging. The World Health Organization's (WHO) policy framework (2015 …

Agricultural activities and risk of Alzheimer's disease: the TRACTOR project, a nationwide retrospective cohort study

P Petit, E Gondard, G Gandon, O Moreaud… - European journal of …, 2024 - Springer
Data regarding Alzheimer's disease (AD) occurrence in farming populations is lacking. This
study aimed to investigate whether, among the entire French farm manager (FM) workforce …

Using a two-sample Mendelian randomization analysis to explore the relationship between physical activity and Alzheimer's disease

B Zhang, X Huang, X Wang, X Chen, C Zheng… - Scientific reports, 2022 - nature.com
Evidence from previous epidemiological studies on the effect of physical activity on the risk
of Alzheimer's disease (AD) is conflicting. We performed a two-sample Mendelian …

Topical Cellular/Tissue and Molecular Aspects Regarding Nonpharmacological Interventions in Alzheimer's Disease—A Systematic Review

S Aurelian, A Ciobanu, R Cărare, SI Stoica… - International Journal of …, 2023 - mdpi.com
One of the most complex and challenging developments at the beginning of the third
millennium is the alarming increase in demographic aging, mainly—but not exclusively …