The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …

Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All
potential pharmacological interventions have failed in clinical trials, meaning that symptom …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Focal cerebral ischaemia and post-ischaemic reperfusion cause cerebral capillary
dysfunction, resulting in oedema formation and haemorrhagic conversion. There are …

Neuroprotection for ischemic stroke refers to strategies, applied singly or in combination, that
antagonize the injurious biochemical and molecular events that eventuate in irreversible …

Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

1. Stroke is the neurological evidence of a critical reduction of cerebral blood flow in a
circumscribed part of the brain, resulting from the sudden or gradually progressing …

Aquaporins (AQPs) are water channel proteins that are essential to life, being expressed in
all kingdoms. In humans, there are 13 AQPs, at least one of which is found in every organ …

Spreading depolarization (SD) is a phenomenon of various cerebral gray matter structures
that only occurs under pathological conditions. In the present paper, we summarize the …