The purpose of this research study was to prepare and characterize cardamom extract-
loaded gelatin nanoparticles (CE-loaded GNPs) with a diameter≤ 200 nm as a potent drug …

Major facilitator superfamily domain‐containing protein‐2a (Mfsd2a) which was considered
as an orphan transporter has recently gained attention for its regulatory role in the …

The blood-brain barrier (BBB) is a protective and semipermeable border of endothelial cells
that prevents toxins and foreign bodies to enter and damage the brain. Unfortunately, the …

Brown adipose tissue (BAT) activation reduces body fat and metabolic disorders by the
enhanced combustion of lipids and glucose into heat. The thermogenic activity of brown …

The blood–brain barrier (BBB) is a major obstacle that prevents therapeutic drugs or genes
from being delivered to the central nervous system. Therefore, it is important to develop …

Targeting a single molecule or a single pathway and poor drug delivery to the brain hamper
the therapy of Alzheimer's disease (AD) based on abnormal metabolism of amyloid-β (Aβ) …

Tailored nanocarriers have gained huge research focus for brain drug delivery, aimed at
combating several neuro-oncological conditions, such as the glioblastoma multiforme …

Carbon‐based nanomaterials (CNMs) are being explored for neurological applications.
However, systematic in vivo studies investigating the effects of CNM nanocarriers in the …

Secondary insult from cerebral ischemia-reperfusion injury (CIRI) is a major risk factor for
poor prognosis of cerebral ischemia. Saponins are steroid or triterpenoid glycosides with …

Abstract Development of safe and efficient non-viral vectors to deliver DNA into the CNS
represents a huge challenge to face many neurological disorders. We elaborated niosomes …