An integrated strategy for ascertaining quality marker of Schisandra chinensis (Turcz.) Baill based on correlation analysis between depression-related monoaminergic …

Y Zhang, X Lv, R Liu, M Zhang, H Liu, H Gao… - … of Chromatography a, 2019 - Elsevier
Abstract Traditional Chinese Medicines (TCMs) have been widely used in orient countries
for thousands of years, while their inconsistent quality and therapy issues have become …

A Nanogel with Effective Blood‐Brain Barrier Penetration Ability through Passive and Active Dual‐Targeting Function

J Liu, M Li, Y Huang, L Zhang, W Li… - Journal of …, 2021 - Wiley Online Library
Clinically, surgery assisted by chemotherapy is the most effective treatment of cancer. But
from our clinical observation, the median survival of patients with glioblastoma is still not so …

[HTML][HTML] Hyperosmotic treatment synergistically boost efficiency of cell-permeable peptides

H Wang, M Zhang, F Zeng, C Liu - Oncotarget, 2016 - ncbi.nlm.nih.gov
Therapeutics delivery into cells has been hurdled due to the barrier of cytoplasmic
membrane. Although cell penetrating peptide (CPP) can potentially serve as an intracellular …

Nanomaterial-based in vitro analytical system for diagnosis and therapy in microfluidic device

JH Choi, J Lee, BK Oh - Biochip journal, 2016 - Springer
Nanomaterials have several advantages in detecting several biomaterials and in enhancing
signals and their inherent effects. Thus, they have been widely applied in the biomedical …

Towards tailored management of malignant brain tumors with nanotheranostics

J Aparicio-Blanco, AI Torres-Suárez - Acta Biomaterialia, 2018 - Elsevier
Malignant brain tumors still represent an unmet medical need given their rapid progression
and often fatal outcome within months of diagnosis. Given their extremely heterogeneous …

Targeting PI3K/Akt in Cerebral Ischemia Reperfusion Injury Alleviation: From Signaling Networks to Targeted Therapy

T Zheng, T Jiang, H Ma, Y Zhu, M Wang - Molecular Neurobiology, 2024 - Springer
Abstract Ischemia/reperfusion (I/R) injury is a pathological event that results in reperfusion
due to low blood flow to an organ. Cerebral ischemia is a common cerebrovascular disease …

Nanotechnology-based approach for enhanced bioavailability and stability of tea polyphenols—a review

RTP Upputuri, K Kulandaivelu, AKA Mandal - Studies in Natural Products …, 2016 - Elsevier
Tea, the most consumed nonalcoholic beverage is being used worldwide as a major health
drink due to some of its important constituents like polyphenols, caffeine, theanine, saponin …

Relevant physicochemical descriptors of “soft nanomedicines” to bypass biological barriers

A Nino-Pariente, VJ Nebot… - Current Pharmaceutical …, 2016 - ingentaconnect.com
Herein, we present an overview on the current status of the characterization techniques and
methodologies used to study the physicochemical descriptors that influence the final clinical …

[HTML][HTML] Uptake of polymeric nanoparticles in a human induced pluripotent stem cell-based blood–brain barrier model: Impact of size, material, and protein corona

HN Onyema, M Berger, A Musyanovych, C Bantz… - …, 2021 - pubs.aip.org
The blood–brain barrier (BBB) maintains the homeostasis of the central nervous system,
which is one of the reasons for the treatments of brain disorders being challenging in nature …

Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process

O Escalona-Rayo, P Fuentes-Vazquez… - Drug Development …, 2017 - Taylor & Francis
Polyglutamine (polyQ) diseases are a class of neurodegenerative disorders that cause
cellular dysfunction and, eventually, neuronal death in specific regions of the brain …