[HTML][HTML] Herbal/natural compounds resist hallmarks of brain aging: From molecular mechanisms to therapeutic strategies

J Qiao, C Wang, Y Chen, S Yu, Y Liu, S Yu, L Jiang… - Antioxidants, 2023 - mdpi.com
Aging is a complex process of impaired physiological integrity and function, and is
associated with increased risk of cardiovascular disease, diabetes, neurodegeneration, and …

[HTML][HTML] Early alterations in structural and functional properties in the neuromuscular junctions of mutant FUS mice

MA Mukhamedyarov, AN Khabibrakhmanov… - International Journal of …, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is manifested as skeletal muscle denervation, loss of
motor neurons and finally severe respiratory failure. Mutations of RNA-binding protein FUS …

KATP channels as ROS-dependent modulator of neurotransmitter release at the neuromuscular junctions

AN Tsentsevitsky, CR Gafurova, AM Petrov - Life Sciences, 2022 - Elsevier
Aims Neurotransmitter release requires high energy demands, making the nerve terminals
metabolically fragile and susceptible to oxidative stress. ATP-sensitive potassium (K ATP) …

Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels

D Kong, L Du, R Liu, T Yuan, S Wang, Y Wang… - Acta Pharmacologica …, 2024 - nature.com
Dopaminergic neurons in the substantia nigra (SN) expressing SUR1/Kir6. 2 type ATP-
sensitive potassium channels (K-ATP) are more vulnerable to rotenone or metabolic stress …

[HTML][HTML] Inhibition of mitochondrial calcium uptake by Ru360 enhances the effect of 1800 MHz radio-frequency electromagnetic fields on DNA damage

C Sun, L Zhu, H Qin, H Su, J Zhang, S Wang… - Ecotoxicology and …, 2023 - Elsevier
Today, the existence of radio-frequency electromagnetic fields (RF-EMF) emitted from cell
phones, wireless routers, base stations, and other sources are everywhere around our living …

[HTML][HTML] The impact of ATP-sensitive potassium channel modulation on mitochondria in a Parkinson's disease model using SH-SY5Y cells depends on their …

A Evinova, E Baranovicova, D Hajduchova… - Journal of Bioenergetics …, 2024 - Springer
Inward rectifying potassium channels sensitive to ATP levels (KATP) have been the subject
of investigation for several decades. Modulators of KATP channels are well-established …

[HTML][HTML] Expression and influence of KATP in umbilical artery smooth muscle cells of patients with hypertensive disorders of pregnancy

B Yin, X Yu, X Fu, X Liu, J Xiao, L Yu, Y Nie… - Scientific Reports, 2024 - nature.com
The objective of this study is to investigate the expression and influence of adenosine
triphosphate-sensitive potassium channel (KATP) in human umbilical arterial smooth muscle …

[HTML][HTML] The ATP-sensitive potassium channel: A therapeutic target for neurodegeneration?

X Xiao, M Bi, X Du, H Jiang - Expert Opinion on Therapeutic …, 2023 - Taylor & Francis
In 1983, NOMA first discovered ATP sensitive potassium channels (KATP channels) through
patch clamp technology, which are widely distributed in the brain and can couple cell energy …

Investigating the role of Polyphenols from Pleurospermum candollei (DC.) extract against diabetic nephropathy through modulating inflammatory cytokines and renal …

M Fatima, MR Khan - Journal of Molecular Structure, 2024 - Elsevier
Pleurosepermum candollei is a local vegetable that is traditionally used to cure abdominal
problems, pain, and infertility. The purpose of this study was to evaluate the therapeutic …

Les canaux potassiques, des cibles pour des médicaments aux indications thérapeutiques variées

P Coudert - Actualités Pharmaceutiques, 2024 - Elsevier
Les canaux potassiques, canaux ioniques les plus répandus chez presque tous les êtres
vivants, se différencient selon leur mode de fonctionnement: activés par le calcium, à …