Anti-CTLA-4 nanobody as a promising approach in cancer immunotherapy

M Babamohamadi, N Mohammadi, E Faryadi… - Cell Death & …, 2024 - nature.com
Cancer is one of the most common diseases and causes of death worldwide. Since common
treatment approaches do not yield acceptable results in many patients, developing …

Iterative community-driven development of a SARS-CoV-2 tissue simulator

M Getz, Y Wang, G An, M Asthana, A Becker… - BioRxiv, 2020 - biorxiv.org
The 2019 novel coronavirus, SARS-CoV-2, is an emerging pathogen of critical significance
to international public health. Knowledge of the interplay between molecular-scale virus …

Dynamic behavior of a general stochastic HIV model with virus-to-cell infection, cell-to-cell transmission, immune response and distributed delays

Y Wang, M Lu, D Jiang - Journal of Nonlinear Science, 2023 - Springer
In this paper, we construct a general four-dimensional delayed HIV infection model with
virus-to-cell infection, cell-to-cell transmission, CTL immune response and parameter …

Dynamics of prey–predator model with stage structure in prey including maturation and gestation delays

B Dubey, A Kumar - Nonlinear Dynamics, 2019 - Springer
This study proposes a three-dimensional prey–predator model with stage structure in prey
(immature and mature) including maturation delay in prey population and gestation delay in …

Threshold dynamics of HCV model with cell-to-cell transmission and a non-cytolytic cure in the presence of humoral immunity

S Pan, SP Chakrabarty - … in Nonlinear Science and Numerical Simulation, 2018 - Elsevier
A mathematical model for HCV infection, which incorporates both the routes of infection
spread, namely, virus-to-cell and cell-to-cell transmission along with a cure rate of infected …

A viral co-infection model with general infection rate in deterministic and stochastic environments

Z Shi, D Jiang - Communications in Nonlinear Science and Numerical …, 2023 - Elsevier
In this paper, we present a model of infection in which a virus can simultaneously infect two
types of target cells. The model has a general form of infection rates in deterministic and …

Environmental variability in a stochastic HIV infection model

Z Shi, D Jiang - Communications in Nonlinear Science and Numerical …, 2023 - Elsevier
In this paper, a stochastic HIV infection model with the Ornstein–Uhlenbeck process is
established and studied. It is assumed that the death rate of healthy CD4+ T cells satisfies …

Virus dynamic behavior of a stochastic HIV/AIDS infection model including two kinds of target cell infections and CTL immune responses

K Qi, D Jiang, T Hayat, A Alsaedi - Mathematics and Computers in …, 2021 - Elsevier
This study investigated the impact of white noise on the HIV/AIDS model with a cytotoxic T
lymphocyte (CTL) immune response. The model introduced the interactions between the …

An HIV stochastic model with cell-to-cell infection, B-cell immune response and distributed delay

Y Wang, J Liu, X Zhang, JM Heffernan - Journal of Mathematical Biology, 2023 - Springer
In this study, a delayed HIV stochastic model with virus-to-cell infection, cell-to-cell
transmission and B-cell immune response is proposed. We first transform the stochastic …

Stationary distribution of an HIV model with general nonlinear incidence rate and stochastic perturbations

Y Wang, D Jiang, T Hayat, A Alsaedi - Journal of the Franklin Institute, 2019 - Elsevier
We present a stochastic HIV infection model with logistic target cell growth, general
nonlinear incidence rate, CTL immune response and parameter perturbations. Through a …