Background: Emotional dysregulation (ED) is a transdiagnostic construct defined as the
inability to regulate the intensity and quality of emotions (such as, fear, anger, sadness), in …

Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …

Background Bipolar disorder (BD) is a severe mental disorder characterized by mood
swings and functional impairment. Although alterations in emotional regulation (ER) are a …

The re-emergence (ie 'breakthrough') of depressive symptoms despite maintenance
treatment of depression with antidepressant drugs is a complex clinical phenomenon …

Background Lithium is an old proven medication, but it is infrequently used in current
practice. This review examines evidence for its benefits and risks and provides clinical …

Background Affective temperaments represent the stable, biologically determined substrates
of mood disorders. The relationship between affective temperaments and bipolar disorder …

Abstract Attention-Deficit/Hyperactivity Disorder (ADHD), Bipolar Disorder (BD) and Alcohol
Use Disorder (AUD) are common medical conditions often coexisting and exerting mutual …

This review is intended to guide primary care providers in differentiating patients with bipolar
depression from those with unipolar depression and inform patient management. Up to 64 …

Background: Bipolar Disorder (BD) is a highly comorbid condition, and rates of cooccurring
disorders are even higher in youth. Comorbid disorders strongly affect clinical presentation …

BackgroundRatings of affective temperament types show promise in helping to differentiate
diagnostic groups among major affective disorders as well as to predict associations with …