A 24-month updated analysis of the comparative effectiveness of ZUMA-5 (axi-cel) vs. SCHOLAR-5 external control in relapsed/refractory follicular lymphoma
Background In the ZUMA-5 trial (Clinical trials identification: NCT03105336), axicabtagene
ciloleucel (axi-cel; a chimeric antigen receptor T-cell therapy) demonstrated high rates of …
ciloleucel (axi-cel; a chimeric antigen receptor T-cell therapy) demonstrated high rates of …
Efficacy comparison of tisagenlecleucel vs usual care in patients with relapsed or refractory follicular lymphoma
G Salles, SJ Schuster, M Dreyling, L Fischer… - Blood …, 2022 - ashpublications.org
The ELARA trial indicates tisagenlecleucel (tisa-cel) is an effective anti-CD19 chimeric
antigen receptor T-cell therapy for relapsed or refractory follicular lymphoma (r/r FL). As …
antigen receptor T-cell therapy for relapsed or refractory follicular lymphoma (r/r FL). As …
Chimeric antigen receptor T-cells in indolent lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia
PS Shah, CA Jacobson - Hematology/Oncology Clinics, 2023 - hemonc.theclinics.com
Indolent B-cell non-Hodgkin lymphomas (B-NHL), chronic lymphocytic leukemia (CLL), and
mantle cell lymphoma (MCL) are widely treatable but typically incurable with conventional …
mantle cell lymphoma (MCL) are widely treatable but typically incurable with conventional …
[HTML][HTML] Treatment patterns and outcomes in relapsed/refractory follicular lymphoma: results from the international SCHOLAR-5 study
The SCHOLAR-5 study examines treatment patterns and outcomes of real-world follicular
lymphoma (FL) patients on 3 rd line of treatment (LoT) or higher, for whom existing data are …
lymphoma (FL) patients on 3 rd line of treatment (LoT) or higher, for whom existing data are …
Phase 3 SELENE study: ibrutinib plus BR/R-CHOP in previously treated patients with follicular or marginal zone lymphoma
LJ Nastoupil, G Hess, MA Pavlovsky… - Blood …, 2023 - ashpublications.org
The phase 3 SELENE study evaluated ibrutinib+ chemoimmunotherapy (CIT; bendamustine
and rituximab [BR]; or rituximab, cyclophosphamide, doxorubicin, vincristine, and …
and rituximab [BR]; or rituximab, cyclophosphamide, doxorubicin, vincristine, and …
Durable response after tisagenlecleucel in adults with relapsed/refractory follicular lymphoma: ELARA trial update
Tisagenlecleucel is approved for adults with relapsed/refractory (r/r) follicular lymphoma (FL)
in the third-or later-line setting. The primary analysis (median follow-up, 17 months) of the …
in the third-or later-line setting. The primary analysis (median follow-up, 17 months) of the …
[HTML][HTML] Matching-adjusted indirect comparison from the Lymphoma Epidemiology of Outcomes Consortium for Real World Evidence (LEO CReWE) study to a clinical …
MJ Maurer, C Casulo, MC Larson, TM Habermann… - …, 2024 - ncbi.nlm.nih.gov
Mosunetuzumab is a novel bispecific antibody targeting epitopes on CD3 on T cells and
CD20 on B cells with the goal of inducing T-cell mediated elimination of malignant B cells. A …
CD20 on B cells with the goal of inducing T-cell mediated elimination of malignant B cells. A …
Epcoritamab monotherapy in patients with relapsed or refractory follicular lymphoma (EPCORE NHL-1): a phase 2 cohort of a single-arm, multicentre study
Background A standard of care and optimal duration of therapy have not been established
for patients with multiply relapsed or refractory follicular lymphoma. The aim of this study was …
for patients with multiply relapsed or refractory follicular lymphoma. The aim of this study was …
Management and clinical outcomes of follicular lymphoma across continuous lines of treatments: a retrospective analysis in China
J Liu, Y Hu, L Zhao, R Nuersulitan, Y Liu, H Yu… - Frontiers in …, 2023 - frontiersin.org
Background Follicular lymphoma (FL) is characterized by an incurable course that frequently
necessitates multiple lines of treatment. While a range of new approaches have broadened …
necessitates multiple lines of treatment. While a range of new approaches have broadened …
[HTML][HTML] Utilization of Real-World Data to Facilitate Clinical Trials for Patients with Lymphoma
The future directions in leveraging real-world evidence (RWE) and real-world data (RWD) in
the field of lymphoma, as compared to traditional experimental clinical trials, are poised to …
the field of lymphoma, as compared to traditional experimental clinical trials, are poised to …