[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential
YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …
Novel therapeutic approaches for Alzheimer's disease: an updated review
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/TLR4/NF-κB pathways in BV2 cells
J Zhang, Y Zheng, Y Luo, Y Du, X Zhang, J Fu - Molecular immunology, 2019 - Elsevier
Highlights•Curcumin reversed LPS-induced decrease in BV2 cell viability and
morphological changes.•Curcumin promoted microglial polarization from the M1 to the M2 …
morphological changes.•Curcumin promoted microglial polarization from the M1 to the M2 …
Management of oxidative stress and other pathologies in Alzheimer's disease
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder, characterized by
the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron …
the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron …
Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders
H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …
Curcumin-primed exosomes potently ameliorate cognitive function in AD mice by inhibiting hyperphosphorylation of the Tau protein through the AKT/GSK-3β pathway
H Wang, H Sui, Y Zheng, Y Jiang, Y Shi, J Liang… - Nanoscale, 2019 - pubs.rsc.org
Alzheimer's disease (AD) is the progressive development of fatal neurodegenerative
diseases. Owing to the unclearness of the pathogenesis of AD and the failure of the drug to …
diseases. Owing to the unclearness of the pathogenesis of AD and the failure of the drug to …
Polyphenols: A first evidence in the synergism and bioactivities
Polyphenols are natural compounds and the most plentiful with synergistic properties
contributing to potential health benefits. This review describes the synergistic interactions of …
contributing to potential health benefits. This review describes the synergistic interactions of …
Protective effects of Indian spice curcumin against amyloid-β in Alzheimer's disease
PH Reddy, M Manczak, X Yin… - Journal of …, 2018 - content.iospress.com
The purpose of our article is to assess the current understanding of Indian spice, curcumin,
against amyloid-ß (Aß)-induced toxicity in Alzheimer's disease (AD) pathogenesis. Natural …
against amyloid-ß (Aß)-induced toxicity in Alzheimer's disease (AD) pathogenesis. Natural …
Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose–response meta-analysis of …
MJ Dehzad, H Ghalandari, M Nouri, M Askarpour - Cytokine, 2023 - Elsevier
Turmeric and its prominent bioactive compound, curcumin, have been the subject of many
investigations with regard to their impact on inflammatory and oxidative balance in the body …
investigations with regard to their impact on inflammatory and oxidative balance in the body …
Curcumin's nanomedicine formulations for therapeutic application in neurological diseases
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …