Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …

Dyslipidaemia is a hallmark of chronic kidney disease (CKD). The severity of dyslipidaemia
not only correlates with CKD stage but is also associated with CKD-associated …

Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …

Diabetic retinopathy (DR), the leading cause of blindness in working-age adults, is one of
the most common complications of diabetes mellitus (DM) featured by metabolic disorders …

BACKGROUND In this study, we identified the lipidomic predictors of early type 2 diabetic
kidney disease (DKD) progression, which are currently undefined. METHODS This …

Diabetic retinal disease (DRD), the most common complication of diabetes and a leading
cause of blindness in working age individuals, is now understood to be a form of sensory …

Peripheral neuropathy (PN) is a complication of prediabetes and type 2 diabetes (T2D).
Increasing evidence suggests that factors besides hyperglycaemia contribute to PN …

Objective The serum lipidomic profile associated with neuropathy in type 2 diabetes is not
well understood. Obesity and dyslipidemia are known neuropathy risk factors, suggesting …

Networks effectively capture interactions among components of complex systems, and have
thus become a mainstay in many scientific disciplines. Growing evidence, especially from …

The sequelae of diabetes include microvascular complications such as diabetic kidney
disease (DKD), which involves glucose-mediated renal injury associated with a disruption in …