Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

SA Bonini, M Premoli, S Tambaro, A Kumar… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Cannabis sativa L.(C. sativa) is an annual dioecious plant,
which shares its origins with the inception of the first agricultural human societies in Asia …

[HTML][HTML] Cannabis sativa: the plant of the thousand and one molecules

CM Andre, JF Hausman, G Guerriero - Frontiers in plant science, 2016 - frontiersin.org
Cannabis sativa L. is an important herbaceous species originating from Central Asia, which
has been used in folk medicine and as a source of textile fiber since the dawn of times. This …

Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview

P Kumar, DK Mahato, M Kamle, R Borah… - Phytotherapy …, 2021 - Wiley Online Library
Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational
and medicinal purposes. In many countries, cannabis‐based medicines have been …

Closing the yield gap for cannabis: a meta-analysis of factors determining cannabis yield

R Backer, T Schwinghamer, P Rosenbaum… - Frontiers in plant …, 2019 - frontiersin.org
Until recently, the commercial production of Cannabis sativa was restricted to varieties that
yielded high-quality fiber while producing low levels of the psychoactive cannabinoid …

Target regulation of PI3K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis

S Giacoppo, F Pollastro, G Grassi, P Bramanti… - Fitoterapia, 2017 - Elsevier
This study was aimed to investigate whether treatment with purified cannabidiol (CBD) may
counteract the development of experimental multiple sclerosis (MS), by targeting the …

[HTML][HTML] A phase 2 randomised clinical trial assessing the tolerability of two different ratios of medicinal cannabis in patients with high grade gliomas

J Schloss, J Lacey, M Sughrue, C Teo - Frontiers in oncology, 2021 - frontiersin.org
Background Cannabis for cancer is very topical and, given the use of illicit cannabis
preparations used in this vulnerable population, research investigating standardised, quality …

Sativex in the management of multiple sclerosis-related spasticity: An overview of the last decade of clinical evaluation

S Giacoppo, P Bramanti, E Mazzon - Multiple sclerosis and related …, 2017 - Elsevier
Background Spasticity is a common symptom of multiple sclerosis (MS) affecting about 80%
of MS patients. Numerous lines of evidence suggest that spasticity due to its complexity is …

Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica

J Ma, Y Gu, P Xu - Communications Biology, 2022 - nature.com
Engineering microbes to produce plant-derived natural products provides an alternate
solution to obtain bioactive products. Here we report a systematic approach to sequentially …

Phytochemicals as adjunctive with conventional anticancer therapies

M Hosein Farzaei, R Bahramsoltani… - Current …, 2016 - ingentaconnect.com
Background: Cancer is defined as the abnormal proliferations of cells which could occur in
any tissue and can cause life-threatening malignancies with high financial costs for both …

Natural phytochemicals in the treatment and prevention of dementia: An overview

R Libro, S Giacoppo, T Soundara Rajan, P Bramanti… - Molecules, 2016 - mdpi.com
The word dementia describes a class of heterogeneous diseases which etiopathogenetic
mechanisms are not well understood. There are different types of dementia, among which …