Computational methods and online resources for identification of piRNA-related molecules

Y Liu, A Li, G Xie, G Liu, X Hei - Interdisciplinary sciences: computational …, 2021 - Springer
Abstract piRNAs are a class of small non-coding RNA molecules, which interact with the
PIWI family and have many important and diverse biological functions. The present review is …

[HTML][HTML] piRNAs and PIWI proteins as diagnostic and prognostic markers of genitourinary cancers

K Hanusek, S Poletajew, P Kryst… - Biomolecules, 2022 - mdpi.com
piRNAs (PIWI-interacting RNAs) are small non-coding RNAs capable of regulation of
transposon and gene expression. piRNAs utilise multiple mechanisms to affect gene …

[HTML][HTML] Cargo small non-coding RNAs of extracellular vesicles isolated from uterine fluid associate with endometrial receptivity and implantation success

T Li, EM Greenblatt, MEJ Shin, TJ Brown, C Chan - Fertility and Sterility, 2021 - Elsevier
Objective To optimize a method of isolating extracellular vesicles (EVs) from uterine fluid
and to characterize small non-coding RNAs (sncRNAs) from the EVs, with the goal of …

Extracellular vesicles for precision medicine in prostate cancer–Is it ready for clinical translation?

H Robinson, MJ Roberts, RA Gardiner… - Seminars in Cancer …, 2023 - Elsevier
Biofluid-based biomarker tests hold great promise for precision medicine in prostate cancer
(PCa) clinical practice. Extracellular vesicles (EV) are established as intercellular …

[HTML][HTML] Non-coding RNAs set a new phenotypic frontier in prostate cancer metastasis and resistance

J Altschuler, JA Stockert, N Kyprianou - International Journal of Molecular …, 2021 - mdpi.com
Prostate cancer (PCa) mortality remains a significant public health problem, as advanced
disease has poor survivability due to the development of resistance in response to both …

[HTML][HTML] PIWI‑interacting RNA in cancer: Molecular mechanisms and possible clinical implications

C Yuan, H Qin, M Ponnusamy… - Oncology …, 2021 - spandidos-publications.com
PIWI‑interacting RNA is a class of non‑coding small RNA that is~ 30 nt long and is primarily
found in mammalian germ cells from mice and humans. In cooperation with the members of …

[HTML][HTML] Identification of key genes associated with cancer stem cell characteristics in Wilms' tumor based on bioinformatics analysis

C Su, J Zheng, S Chen, J Tuo, J Su, X Ou… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Nephroblastoma, also known as Wilms' tumor (WT), remains one of the major
causes of tumor-related deaths worldwide in children. Cancer stem cells (CSCs) are …

Small non‐coding RNA sequencing reveals global dysregulation of piwi‐interacting RNA (piRNA) expression in gonadal malignant germ cell tumours

S Laidlaw, L Alonso‐Crisostomo, S Bailey… - …, 2023 - Wiley Online Library
Background Analyses of small non‐coding RNA (ncRNA) expression in malignant germ cell
tumours (GCTs) have focused on microRNAs (miRNAs). As GCTs all arise from primordial …

piRNAQuest V. 2: an updated resource for searching through the piRNAome of multiple species

B Ghosh, A Sarkar, S Mondal, N Bhattacharya… - RNA biology, 2022 - Taylor & Francis
ABSTRACT PIWI interacting RNAs (piRNAs) have emerged as important gene regulators in
recent times. Since the release of our first version of piRNAQuest in 2014, lots of novel …

Candidate l‐methionine target piRNA regulatory networks analysis response to cocaine‐conditioned place preference in mice

K Zhang, G Ji, M Zhao, Y Wang - Brain and Behavior, 2021 - Wiley Online Library
Background Methionine has been proven to inhibit addictive behaviors of cocaine
dependence. However, the mechanism of methionine response to cocaine CPP is unknown …