[HTML][HTML] Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages
E Ghasemian, N Faal, H Pickering… - Microbial …, 2024 - microbiologyresearch.org
Trachoma, a neglected tropical disease caused by Chlamydia trachomatis (Ct) serovars A–
C, is the leading infectious cause of blindness worldwide. Africa bears the highest burden …
C, is the leading infectious cause of blindness worldwide. Africa bears the highest burden …
Clinical persistence of Chlamydia trachomatis sexually transmitted strains involves novel mutations in the functional αββα tetramer of the tryptophan synthase operon
Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a
major public health concern. In vitro persistence is known to develop through interferon …
major public health concern. In vitro persistence is known to develop through interferon …
Genomics of Ocular Chlamydia trachomatis After 5 Years of SAFE Interventions for Trachoma in Amhara, Ethiopia
H Pickering, A Chernet, E Sata… - The Journal of …, 2022 - academic.oup.com
Background To eliminate trachoma as a public health problem, the World Health
Organization recommends the SAFE (surgery, antibiotics, facial cleanliness, and …
Organization recommends the SAFE (surgery, antibiotics, facial cleanliness, and …
[HTML][HTML] A systems serology approach to the investigation of infection-induced antibody responses and protection in trachoma
A Barton, I Rosenkrands, H Pickering, N Faal… - Frontiers in …, 2023 - frontiersin.org
Background Ocular infections with Chlamydia trachomatis serovars A–C cause the
neglected tropical disease trachoma. As infection does not confer complete immunity …
neglected tropical disease trachoma. As infection does not confer complete immunity …
[HTML][HTML] Prevalence and circulant genotypes of Chlamydia trachomatis in university women from cities in the Brazilian Amazon
LM Dos Santos, MRMS Vieira, RC Vieira, LBL Silva… - Plos one, 2024 - journals.plos.org
Background Approximately 80% of infected women infected by Chlamydia trachomatis are
asymptomatic, although this infection can lead to serious complications in the female …
asymptomatic, although this infection can lead to serious complications in the female …
[HTML][HTML] Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating …
EM Harding-Esch, MJ Holland, JF Schémann… - Parasites & vectors, 2019 - Springer
Background Mass drug administration (MDA) with azithromycin is a cornerstone of the
trachoma elimination strategy. Although the global prevalence of active trachoma has …
trachoma elimination strategy. Although the global prevalence of active trachoma has …
[HTML][HTML] Whole-genome sequencing of ocular Chlamydia trachomatis isolates from Gadarif State, Sudan
Background Trachoma, caused by ocular Chlamydia trachomatis, is the leading infectious
cause of blindness worldwide. Sudan first reported trachoma in the 1930s and has since …
cause of blindness worldwide. Sudan first reported trachoma in the 1930s and has since …
[HTML][HTML] Genetic Transformation of a C. trachomatis Ocular Isolate With the Functional Tryptophan Synthase Operon Confers an Indole-Rescuable Phenotype
CE O'Neill, RJ Skilton, SA Pearson, S Filardo… - Frontiers in cellular …, 2018 - frontiersin.org
Chlamydia trachomatis is the leading cause of preventable blindness and the most common
bacterial sexually transmitted infection. Different strains are associated with ocular or …
bacterial sexually transmitted infection. Different strains are associated with ocular or …
Whole-genome enrichment and sequencing of Chlamydia trachomatis directly from patient clinical vaginal and rectal swabs
KE Bowden, SJ Joseph, JC Cartee, N Ziklo, D Danavall… - Msphere, 2021 - Am Soc Microbiol
Chlamydia trachomatis, an obligately intracellular bacterium, is the most prevalent cause of
bacterial sexually transmitted infections (STIs) worldwide. Numbers of US infections of the …
bacterial sexually transmitted infections (STIs) worldwide. Numbers of US infections of the …
High prevalence and circulant genotypes of Chlamydia trachomatis in vulnerable university women from four cities in the Brazilian Amazon
LM dos Santos, RC Vieira, LB da Luz Silva… - 2022 - researchsquare.com
Background Approximately 80% of infected women infected by Chlamydia trachomatis are
asymptomatic, although this infection can lead to serious complications in the female …
asymptomatic, although this infection can lead to serious complications in the female …