Inhaled therapy in respiratory disease: the complex interplay of pulmonary kinetic processes

JM Borghardt, C Kloft, A Sharma - Canadian respiratory journal, 2018 - Wiley Online Library
The inhalation route is frequently used to administer drugs for the management of
respiratory diseases such as asthma or chronic obstructive pulmonary disease. Compared …

Choosing the right inhaler for your asthma or COPD patient

OS Usmani - Therapeutics and clinical risk management, 2019 - Taylor & Francis
Appropriate selection and correct use of inhalation devices is an integral component in the
management of asthma and chronic obstructive pulmonary disease (COPD). It is well known …

Objective assessment of adherence to inhalers by patients with chronic obstructive pulmonary disease

I Sulaiman, B Cushen, G Greene, J Seheult… - American journal of …, 2017 - atsjournals.org
Rationale: Objective adherence to inhaled therapy by patients with chronic obstructive
pulmonary disease (COPD) has not been reported. Objectives: To objectively quantify …

[HTML][HTML] Optimizing drug delivery in COPD: the role of inhaler devices

P Rogliani, L Calzetta, A Coppola, F Cavalli, J Ora… - Respiratory …, 2017 - Elsevier
Background Inhaled medication is the cornerstone of the pharmacological treatment for
patients with asthma and chronic obstructive pulmonary disease (COPD). Several inhaler …

The climate is changing for metered-dose inhalers and action is needed

JN Pritchard - Drug Design, Development and Therapy, 2020 - Taylor & Francis
Increases in global temperature are already having a significant impact on our climate. The
hydrofluorocarbon (HFC) propellants used today in pressurized metered-dose inhalers …

Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease

M Cazzola, F Cavalli, OS Usmani… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …

[HTML][HTML] The role of inspiratory flow in selection and use of inhaled therapy for patients with chronic obstructive pulmonary disease

DA Mahler - Respiratory Medicine, 2020 - Elsevier
Inhalation therapy is the mainstay of chronic obstructive pulmonary disease management,
and inhaler selection can have a profound impact on drug delivery and medication …

A review of nebulized drug delivery in COPD

DP Tashkin - … Journal of Chronic Obstructive Pulmonary Disease, 2016 - Taylor & Francis
Current guidelines recommend inhaled pharmacologic therapy as the preferred route of
administration for treating COPD. Bronchodilators (β2-agonists and antimuscarinics) are the …

Comparison of peak inspiratory flow rate via the Breezhaler®, Ellipta® and HandiHaler® dry powder inhalers in patients with moderate to very severe COPD: a …

P Altman, L Wehbe, J Dederichs, T Guerin… - BMC pulmonary …, 2018 - Springer
Background The chronic and progressive nature of chronic obstructive pulmonary disease
(COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are …

Device use errors with soft mist inhalers: a global systematic literature review and meta-analysis

M Navaie, C Dembek, S Cho-Reyes… - Chronic Respiratory …, 2020 - journals.sagepub.com
Inhaled bronchodilators are the cornerstone of treatment for chronic obstructive pulmonary
disease (COPD). Soft mist inhalers (SMIs) are devices that deliver bronchodilators. Although …