Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

Melatonin is a signal molecule that modulates the biological circadian rhythms of
vertebrates. Melatonin deficiency is thought to be associated with several disorders …

The pineal hormone melatonin influences insulin secretion, as well as glucagon and
somatostatin secretion, both in vivo and in vitro. These effects are mediated by two specific …

Disturbed circadian rhythms have been a risk factor for type 2 diabetes mellitus (T2DM).
Melatonin is the major chronobiotic hormone regulating both circadian rhythm and glucose …

Introduction: Melatonin is a pineal hormone that has acquired several unique modes of
regulating the physiological effects in mammals due to its characteristic phylogenetic history …

Pinealectomy in vertebrates accelerated intervertebral disk degeneration (IDD). However,
the potential mechanisms, particularly melatonin's role, are still to be clarified. In this study …

The potentially beneficial effects of probiotics in the treatment of obesity have been generally
demonstrated. In the present study, a new strain of Lactobacillus reuteri SY523 (L. reuteri …

Melatonin, N-acetyl-5-methoxytryptamine, is an indole mainly synthesized from tryptophan in
the pineal gland and secreted exclusively during the night in all the animals reported to date …

Melatonin is present in mammalian follicular fluid and plays an important role in regulating
steroidogenesis in follicular cells. In this study, we report the effect of melatonin on …

In the past, different human disorders were described by scientists from the perspective of
either environmental factors or just by genetically related mechanisms. The rise in …