[HTML][HTML] Alleviating anxiety and taming trauma: novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder

N Singewald, SB Sartori, A Reif, A Holmes - Neuropharmacology, 2023 - Elsevier
Psychiatric disorders associated with psychological trauma, stress and anxiety are a highly
prevalent and increasing cause of morbidity worldwide. Current therapeutic approaches …

[HTML][HTML] Metabolic and inflammatory response in post-traumatic stress disorder (PTSD): a systematic review on peripheral neuroimmune biomarkers

V Dell'Oste, S Fantasia, D Gravina, L Palego… - International journal of …, 2023 - mdpi.com
Several heterogeneous pathophysiology pathways have been hypothesized for being
involved in the onset and course of Post-Traumatic Stress Disorder (PTSD). This systematic …

The emerging role of the gut microbiome in posttraumatic stress disorder

S Ke, J Hartmann, KJ Ressler, YY Liu… - Brain, behavior, and …, 2023 - Elsevier
Posttraumatic stress disorder (PTSD) occurs in some people following exposure to a
terrifying or catastrophic event involving actual/threatened death, serious injury, or sexual …

Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants

S Katrinli, AK Smith, SS Drury, J Covault, JD Ford… - Epigenetics, 2023 - Taylor & Francis
Pregnancy can exacerbate or prompt the onset of stress-related disorders, such as post-
traumatic stress disorder (PTSD). PTSD is associated with heightened stress responsivity …

Validity of mental and physical stress models

E Hendry, B McCallister, DJ Elman, R Freeman… - Neuroscience & …, 2024 - Elsevier
Different stress models are employed to enhance our understanding of the underlying
mechanisms and explore potential interventions. However, the utility of these models …

Dietary glutamate enhances intestinal immunity by modulating microbiota and Th17/Treg balance-related immune signaling in piglets after lipopolysaccharide …

G Liu, K Gu, X Liu, G Jia, H Zhao, X Chen… - Food Research …, 2023 - Elsevier
The purpose of this study was to explore the effects of glutamate on piglet growth
performance and intestinal immunity function, and to further elucidate its mechanism. In a 2× …

Identifying genetic loci that are associated with changes in gene expression in PTSD in a South African cohort

PC Swart, M Du Plessis, C Rust… - Journal of …, 2023 - Wiley Online Library
The molecular mechanisms underlying posttraumatic stress disorder (PTSD) are yet to be
fully elucidated, especially in underrepresented population groups. Expression quantitative …

[HTML][HTML] Platelets bridging the gap between gut dysbiosis and neuroinflammation in stress-linked disorders: A narrative review

C Rust, S Malan-Muller, LL van den Heuvel… - Journal of …, 2023 - Elsevier
In this narrative review, we examine the association between gut dysbiosis,
neuroinflammation, and stress-linked disorders, including depression, anxiety, and post …

[HTML][HTML] Sex-dependent effects of microglial reduction on impaired fear extinction induced by single prolonged stress

O Torres-Rodriguez, E Ortiz-Nazario… - Frontiers in Behavioral …, 2023 - frontiersin.org
Single prolonged stress (SPS) is a preclinical rodent model for studying post-traumatic
stress disorder (PTSD)-like behaviors. Previously we found that increased expression of the …

[HTML][HTML] Associations between emotional distress, sleep changes, decreased tooth brushing frequency, self-reported oral ulcers and SARS-Cov-2 infection during the …

MO Folayan, RAA Zuniga, OC Ezechi, B Brown… - International journal of …, 2022 - mdpi.com
This study assessed the association between emotional distress, sleep changes, decreased
frequency of tooth brushing, and self-reported oral ulcers, and the association between …