Novel mutations of OGG1 base excision repair pathway gene in laryngeal cancer patients
Abstract OGG1 (The human 8-oxoguanine glycosylase 1) is the primary enzyme in BER
(base excision repair) pathway, responsible for the excision of 7, 8-dihydro-8-oxoguanine (8 …
(base excision repair) pathway, responsible for the excision of 7, 8-dihydro-8-oxoguanine (8 …
Formation, repair, and biological effects of DNA–protein cross-link damage
Genomic DNA is constantly associated with the various proteins that are involved in DNA
folding and transactions. The association between DNA and proteins is reversible, and …
folding and transactions. The association between DNA and proteins is reversible, and …
PARP1 rs1136410 (A/G) polymorphism is associated with early age of onset of gallbladder cancer
Objectives Evaluation of the association of PARP1 rs1136410 (A/G) polymorphism with
gallbladder cancer susceptibility and its prognosis in the Indian population of eastern Uttar …
gallbladder cancer susceptibility and its prognosis in the Indian population of eastern Uttar …
Effect of gliclazide on DNA damage in human peripheral blood lymphocytes and insulinoma mouse cells
A Sliwinska, J Blasiak, J Drzewoski - Chemico-biological interactions, 2006 - Elsevier
Type 2 diabetes mellitus is associated with increased oxidative stress. Free radicals
produced during this stress may damage various cellular components. Gliclazide, a second …
produced during this stress may damage various cellular components. Gliclazide, a second …
广东高本底地区人群氧化损伤及抗氧化水平调查
陈慧峰， 郭强之， 刘明， 耿继武， 苏世标 - 中华放射医学与防护杂志, 2015 - cqvip.com
目的探讨长期连续天然放射性照射对人群氧化损伤及抗氧化水平的影响. 方法选择广东天然
放射性高本底辐射地区(HBRA) 48 名男性居民为研究对象, 选择恩平市某镇(CA) 相匹配的48 …
放射性高本底辐射地区(HBRA) 48 名男性居民为研究对象, 选择恩平市某镇(CA) 相匹配的48 …
In vitro replication and repair of DNA containing a C2 '-oxidized abasic site
MM Greenberg, YN Weledji, KM Kroeger, J Kim - Biochemistry, 2004 - ACS Publications
Abasic lesions are unable to form Watson− Crick hydrogen bonds with nucleotides.
Nonetheless, polymerase and repair enzymes distinguish between various oxidized abasic …
Nonetheless, polymerase and repair enzymes distinguish between various oxidized abasic …
Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster
The eukaryotic DNA polymerase processivity factor, proliferating cell nuclear antigen, is an
essential component in the DNA replication and repair machinery. In Drosophila …
essential component in the DNA replication and repair machinery. In Drosophila …
Transcriptional inhibition by an oxidized abasic site in DNA
Y Wang, TL Sheppard, S Tornaletti… - Chemical research in …, 2006 - ACS Publications
2-Deoxyribonolactone (dL) is an oxidized abasic site in DNA that can be induced by γ-
radiolysis, ultraviolet irradiation, and numerous antitumor drugs. Although this lesion is …
radiolysis, ultraviolet irradiation, and numerous antitumor drugs. Although this lesion is …
Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N …
D Gasparutto, E Muller, S Boiteux, J Cadet - Biochimica et Biophysica Acta …, 2009 - Elsevier
BACKGROUND:(5R⁎) and (5S⁎) diastereomers of 1-[2-deoxy-β-d-erythro-pentofuranosyl]-5-
hydroxyhydantoin (5-OH-dHyd) and 1-[2-deoxy-β-d-erythro-pentofuranosyl]-5-hydroxy-5 …
hydroxyhydantoin (5-OH-dHyd) and 1-[2-deoxy-β-d-erythro-pentofuranosyl]-5-hydroxy-5 …
Lung cancer in smoking patients inversely alters the activity of hOGG1 and hNTH1
Z Radak, S Goto, H Nakamoto, K Udud, Z Papai… - Cancer letters, 2005 - Elsevier
N-Glycosylases excise the damaged adducts from DNA. 7, 8-Dihydro-8-oxoguanine in
human cells is repaired by OGG1 and hNTH1. The activities of hOGG1 and hNTH1 were …
human cells is repaired by OGG1 and hNTH1. The activities of hOGG1 and hNTH1 were …